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Hereditary Optic Neuropathies: Induced Pluripotent Stem Cell-Based 2D/3D Approaches

Inherited optic neuropathies share visual impairment due to the degeneration of retinal ganglion cells (RGCs) as the hallmark of the disease. This group of genetic disorders are caused by mutations in nuclear genes or in the mitochondrial DNA (mtDNA). An impaired mitochondrial function is the underl...

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Detalles Bibliográficos
Autores principales:	García-López, Marta, Arenas, Joaquín, Gallardo, M. Esther
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7831942/ https://www.ncbi.nlm.nih.gov/pubmed/33477675 http://dx.doi.org/10.3390/genes12010112

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