Design of a highly thermotolerant, immunogenic SARS-CoV-2 spike fragment

Virtually all SARS-CoV-2 vaccines currently in clinical testing are stored in a refrigerated or frozen state prior to use. This is a major impediment to deployment in resource-poor settings. Furthermore, several of them use viral vectors or mRNA. In contrast to protein subunit vaccines, there is lim...

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Detalles Bibliográficos
Autores principales: Malladi, Sameer Kumar, Singh, Randhir, Pandey, Suman, Gayathri, Savitha, Kanjo, Kawkab, Ahmed, Shahbaz, Khan, Mohammad Suhail, Kalita, Parismita, Girish, Nidhi, Upadhyaya, Aditya, Reddy, Poorvi, Pramanick, Ishika, Bhasin, Munmun, Mani, Shailendra, Bhattacharyya, Sankar, Joseph, Jeswin, Thankamani, Karthika, Raj, V. Stalin, Dutta, Somnath, Singh, Ramandeep, Nadig, Gautham, Varadarajan, Raghavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832000/
https://www.ncbi.nlm.nih.gov/pubmed/33154165
http://dx.doi.org/10.1074/jbc.RA120.016284

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