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Tracheostomy in patients with SARS-CoV-2 reduces time on mechanical ventilation but not intensive care unit stay

Cross-sectional study to know if tracheostomy influences the time on mechanical ventilation and reduces the ICU stay in patients with SARS-CoV2. From February 14 to May 31, 2020, 29 patients: 23 men and 6 women, with an average age (SD) of 66.4 years (±6,2) required tracheostomy. The average intensi...

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Autores principales: Mata-Castro, Nieves, Sanz-López, Lorena, Pinacho-Martínez, Paloma, Varillas-Delgado, David, Miró-Murillo, Miguel, Martín-Delgado, María Cruz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832018/
https://www.ncbi.nlm.nih.gov/pubmed/33422946
http://dx.doi.org/10.1016/j.amjoto.2020.102867
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author Mata-Castro, Nieves
Sanz-López, Lorena
Pinacho-Martínez, Paloma
Varillas-Delgado, David
Miró-Murillo, Miguel
Martín-Delgado, María Cruz
author_facet Mata-Castro, Nieves
Sanz-López, Lorena
Pinacho-Martínez, Paloma
Varillas-Delgado, David
Miró-Murillo, Miguel
Martín-Delgado, María Cruz
author_sort Mata-Castro, Nieves
collection PubMed
description Cross-sectional study to know if tracheostomy influences the time on mechanical ventilation and reduces the ICU stay in patients with SARS-CoV2. From February 14 to May 31, 2020, 29 patients: 23 men and 6 women, with an average age (SD) of 66.4 years (±6,2) required tracheostomy. The average intensive care unit (ICU) stay was 36 days [31–56.5]. The average days on mechanical ventilation was 28,5 days (±9.7). Mean time to tracheostomy was 15.2 days (±9.5) with an average disconnection time after procedure of 11.3 days (±7.4). The average hospital stay was 55 days [39–79]. A directly proportional relation between the number of days of MV and the number of days from ICU admission until tracheostomy showed a significant value of p = 0.008. For each day of delay in tracheostomy, the days of mechanical ventilation were increased by 0.6 days. There was no relation between days to tracheostomy and days to disconnection (p = 0.092). PaO2 / FiO2 (PAFI) before tracheostomy and Simplified Acute Physiology Score III (SAPS III) at admission presented a statistical relation with mortality, with an OR of 1.683 (95%CI; 0.926–2.351; p = 0.078) and an OR of 1.312 (CI95%: 1.011–1.703; p = 0.034) respectively. The length of stay in the ICU until the tracheostomy was not related to the risk of death (p = 0.682). PEEP and PaO2/FiO2 (PAFI) at admission and before tracheostomy and APACHE II, SAPS III and SOFA at admission did not show influence over time on MV. We conclude that the delay in tracheostomy increase the days on mechanical ventilation but does not influence stay or mortality.
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spelling pubmed-78320182021-01-26 Tracheostomy in patients with SARS-CoV-2 reduces time on mechanical ventilation but not intensive care unit stay Mata-Castro, Nieves Sanz-López, Lorena Pinacho-Martínez, Paloma Varillas-Delgado, David Miró-Murillo, Miguel Martín-Delgado, María Cruz Am J Otolaryngol Article Cross-sectional study to know if tracheostomy influences the time on mechanical ventilation and reduces the ICU stay in patients with SARS-CoV2. From February 14 to May 31, 2020, 29 patients: 23 men and 6 women, with an average age (SD) of 66.4 years (±6,2) required tracheostomy. The average intensive care unit (ICU) stay was 36 days [31–56.5]. The average days on mechanical ventilation was 28,5 days (±9.7). Mean time to tracheostomy was 15.2 days (±9.5) with an average disconnection time after procedure of 11.3 days (±7.4). The average hospital stay was 55 days [39–79]. A directly proportional relation between the number of days of MV and the number of days from ICU admission until tracheostomy showed a significant value of p = 0.008. For each day of delay in tracheostomy, the days of mechanical ventilation were increased by 0.6 days. There was no relation between days to tracheostomy and days to disconnection (p = 0.092). PaO2 / FiO2 (PAFI) before tracheostomy and Simplified Acute Physiology Score III (SAPS III) at admission presented a statistical relation with mortality, with an OR of 1.683 (95%CI; 0.926–2.351; p = 0.078) and an OR of 1.312 (CI95%: 1.011–1.703; p = 0.034) respectively. The length of stay in the ICU until the tracheostomy was not related to the risk of death (p = 0.682). PEEP and PaO2/FiO2 (PAFI) at admission and before tracheostomy and APACHE II, SAPS III and SOFA at admission did not show influence over time on MV. We conclude that the delay in tracheostomy increase the days on mechanical ventilation but does not influence stay or mortality. Elsevier Inc. 2021 2021-01-04 /pmc/articles/PMC7832018/ /pubmed/33422946 http://dx.doi.org/10.1016/j.amjoto.2020.102867 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Mata-Castro, Nieves
Sanz-López, Lorena
Pinacho-Martínez, Paloma
Varillas-Delgado, David
Miró-Murillo, Miguel
Martín-Delgado, María Cruz
Tracheostomy in patients with SARS-CoV-2 reduces time on mechanical ventilation but not intensive care unit stay
title Tracheostomy in patients with SARS-CoV-2 reduces time on mechanical ventilation but not intensive care unit stay
title_full Tracheostomy in patients with SARS-CoV-2 reduces time on mechanical ventilation but not intensive care unit stay
title_fullStr Tracheostomy in patients with SARS-CoV-2 reduces time on mechanical ventilation but not intensive care unit stay
title_full_unstemmed Tracheostomy in patients with SARS-CoV-2 reduces time on mechanical ventilation but not intensive care unit stay
title_short Tracheostomy in patients with SARS-CoV-2 reduces time on mechanical ventilation but not intensive care unit stay
title_sort tracheostomy in patients with sars-cov-2 reduces time on mechanical ventilation but not intensive care unit stay
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832018/
https://www.ncbi.nlm.nih.gov/pubmed/33422946
http://dx.doi.org/10.1016/j.amjoto.2020.102867
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