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Simultaneous Activation of Erk1/2 and Akt Signaling is Critical for Formononetin-Induced Promotion of Endothelial Function

Formononetin (FMNT) is a major bioactive compound from Astragalus membranaceus (Fisch.) Bunge, and has been widely used to treat conditions related to vascular insufficiency. However, the molecular mechanism for the therapeutic effect has not been well defined. This study aimed to investigate the ef...

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Detalles Bibliográficos
Autores principales: Wu, Jinjun, Kong, Muyan, Lou, Yanmei, Li, Leyan, Yang, Chunlin, Xu, Huifang, Cui, Yuqi, Hao, Hong, Liu, Zhenguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832036/
https://www.ncbi.nlm.nih.gov/pubmed/33505313
http://dx.doi.org/10.3389/fphar.2020.608518