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Predicting mortality risk in patients with COVID-19 using machine learning to help medical decision-making

In the wake of COVID-19 disease, caused by the SARS-CoV-2 virus, we designed and developed a predictive model based on Artificial Intelligence (AI) and Machine Learning algorithms to determine the health risk and predict the mortality risk of patients with COVID-19. In this study, we used a dataset...

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Autores principales: Pourhomayoun, Mohammad, Shakibi, Mahdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832156/
https://www.ncbi.nlm.nih.gov/pubmed/33521226
http://dx.doi.org/10.1016/j.smhl.2020.100178
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author Pourhomayoun, Mohammad
Shakibi, Mahdi
author_facet Pourhomayoun, Mohammad
Shakibi, Mahdi
author_sort Pourhomayoun, Mohammad
collection PubMed
description In the wake of COVID-19 disease, caused by the SARS-CoV-2 virus, we designed and developed a predictive model based on Artificial Intelligence (AI) and Machine Learning algorithms to determine the health risk and predict the mortality risk of patients with COVID-19. In this study, we used a dataset of more than 2,670,000 laboratory-confirmed COVID-19 patients from 146 countries around the world including 307,382 labeled samples. This study proposes an AI model to help hospitals and medical facilities decide who needs to get attention first, who has higher priority to be hospitalized, triage patients when the system is overwhelmed by overcrowding, and eliminate delays in providing the necessary care. The results demonstrate 89.98% overall accuracy in predicting the mortality rate. We used several machine learning algorithms including Support Vector Machine (SVM), Artificial Neural Networks, Random Forest, Decision Tree, Logistic Regression, and K-Nearest Neighbor (KNN) to predict the mortality rate in patients with COVID-19. In this study, the most alarming symptoms and features were also identified. Finally, we used a separate dataset of COVID-19 patients to evaluate our developed model accuracy, and used confusion matrix to make an in-depth analysis of our classifiers and calculate the sensitivity and specificity of our model.
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spelling pubmed-78321562021-01-26 Predicting mortality risk in patients with COVID-19 using machine learning to help medical decision-making Pourhomayoun, Mohammad Shakibi, Mahdi Smart Health (Amst) Article In the wake of COVID-19 disease, caused by the SARS-CoV-2 virus, we designed and developed a predictive model based on Artificial Intelligence (AI) and Machine Learning algorithms to determine the health risk and predict the mortality risk of patients with COVID-19. In this study, we used a dataset of more than 2,670,000 laboratory-confirmed COVID-19 patients from 146 countries around the world including 307,382 labeled samples. This study proposes an AI model to help hospitals and medical facilities decide who needs to get attention first, who has higher priority to be hospitalized, triage patients when the system is overwhelmed by overcrowding, and eliminate delays in providing the necessary care. The results demonstrate 89.98% overall accuracy in predicting the mortality rate. We used several machine learning algorithms including Support Vector Machine (SVM), Artificial Neural Networks, Random Forest, Decision Tree, Logistic Regression, and K-Nearest Neighbor (KNN) to predict the mortality rate in patients with COVID-19. In this study, the most alarming symptoms and features were also identified. Finally, we used a separate dataset of COVID-19 patients to evaluate our developed model accuracy, and used confusion matrix to make an in-depth analysis of our classifiers and calculate the sensitivity and specificity of our model. The Authors. Published by Elsevier Inc. 2021-04 2021-01-16 /pmc/articles/PMC7832156/ /pubmed/33521226 http://dx.doi.org/10.1016/j.smhl.2020.100178 Text en © 2021 The Authors Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Pourhomayoun, Mohammad
Shakibi, Mahdi
Predicting mortality risk in patients with COVID-19 using machine learning to help medical decision-making
title Predicting mortality risk in patients with COVID-19 using machine learning to help medical decision-making
title_full Predicting mortality risk in patients with COVID-19 using machine learning to help medical decision-making
title_fullStr Predicting mortality risk in patients with COVID-19 using machine learning to help medical decision-making
title_full_unstemmed Predicting mortality risk in patients with COVID-19 using machine learning to help medical decision-making
title_short Predicting mortality risk in patients with COVID-19 using machine learning to help medical decision-making
title_sort predicting mortality risk in patients with covid-19 using machine learning to help medical decision-making
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832156/
https://www.ncbi.nlm.nih.gov/pubmed/33521226
http://dx.doi.org/10.1016/j.smhl.2020.100178
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