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Antidiabetic and anticancer activity of Chinese water chestnut (Eleocharis dulcis) extract with multistage extraction
The aims of this research were to observe yield extract, phytochemical content, the antidiabetic and anticancer activity of Chinese water chestnut. This research method used an experimental laboratory, and data analysis was carried out descriptively. The stages carried of this research are sample ex...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832194/ https://www.ncbi.nlm.nih.gov/pubmed/33532353 http://dx.doi.org/10.4103/japtr.JAPTR_67_20 |
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author | Baehaki, Ace Widiastuti, Indah Lestari, Susi Masruro, Masruro Putra, Hemi Adi |
author_facet | Baehaki, Ace Widiastuti, Indah Lestari, Susi Masruro, Masruro Putra, Hemi Adi |
author_sort | Baehaki, Ace |
collection | PubMed |
description | The aims of this research were to observe yield extract, phytochemical content, the antidiabetic and anticancer activity of Chinese water chestnut. This research method used an experimental laboratory, and data analysis was carried out descriptively. The stages carried of this research are sample extraction, extract yield, phytochemical analysis (flavonoid and phenolic content), antidiabetic, and anticancer activity. The results showed that the yield of extract using ethanol on Chinese water chestnut was higher than that extracts using n-hexane and ethyl acetate solvents. Phenolic and flavonoids compounds are polar so that the results of extracts with ethanol solvents show higher values than that extracts using n-hexane and ethyl acetate solvents. The result of antidiabetic activity has the highest value at a concentration of 2000 ppm using ethanol value of 65.74%. The results of the anticancer activity were expressed by (IC(50)), the IC(50) value of the n-hexane extract was 1.231.74 ppm, ethyl acetate 941.04 ppm, and ethanol 2.261.90 ppm. |
format | Online Article Text |
id | pubmed-7832194 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-78321942021-02-01 Antidiabetic and anticancer activity of Chinese water chestnut (Eleocharis dulcis) extract with multistage extraction Baehaki, Ace Widiastuti, Indah Lestari, Susi Masruro, Masruro Putra, Hemi Adi J Adv Pharm Technol Res Original Article The aims of this research were to observe yield extract, phytochemical content, the antidiabetic and anticancer activity of Chinese water chestnut. This research method used an experimental laboratory, and data analysis was carried out descriptively. The stages carried of this research are sample extraction, extract yield, phytochemical analysis (flavonoid and phenolic content), antidiabetic, and anticancer activity. The results showed that the yield of extract using ethanol on Chinese water chestnut was higher than that extracts using n-hexane and ethyl acetate solvents. Phenolic and flavonoids compounds are polar so that the results of extracts with ethanol solvents show higher values than that extracts using n-hexane and ethyl acetate solvents. The result of antidiabetic activity has the highest value at a concentration of 2000 ppm using ethanol value of 65.74%. The results of the anticancer activity were expressed by (IC(50)), the IC(50) value of the n-hexane extract was 1.231.74 ppm, ethyl acetate 941.04 ppm, and ethanol 2.261.90 ppm. Wolters Kluwer - Medknow 2021 2021-01-09 /pmc/articles/PMC7832194/ /pubmed/33532353 http://dx.doi.org/10.4103/japtr.JAPTR_67_20 Text en Copyright: © 2021 Journal of Advanced Pharmaceutical Technology & Research http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Baehaki, Ace Widiastuti, Indah Lestari, Susi Masruro, Masruro Putra, Hemi Adi Antidiabetic and anticancer activity of Chinese water chestnut (Eleocharis dulcis) extract with multistage extraction |
title | Antidiabetic and anticancer activity of Chinese water chestnut (Eleocharis dulcis) extract with multistage extraction |
title_full | Antidiabetic and anticancer activity of Chinese water chestnut (Eleocharis dulcis) extract with multistage extraction |
title_fullStr | Antidiabetic and anticancer activity of Chinese water chestnut (Eleocharis dulcis) extract with multistage extraction |
title_full_unstemmed | Antidiabetic and anticancer activity of Chinese water chestnut (Eleocharis dulcis) extract with multistage extraction |
title_short | Antidiabetic and anticancer activity of Chinese water chestnut (Eleocharis dulcis) extract with multistage extraction |
title_sort | antidiabetic and anticancer activity of chinese water chestnut (eleocharis dulcis) extract with multistage extraction |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832194/ https://www.ncbi.nlm.nih.gov/pubmed/33532353 http://dx.doi.org/10.4103/japtr.JAPTR_67_20 |
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