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Enhancement of Gingival Tissue Adherence of Zirconia Implant Posts: In Vitro Study

Prevention of bacterial inflammation around dental implants (peri-implantitis) is one of the keys to success of the implantation and can be achieved by securing the gingival tissue-abutment interface preventing penetration of bacteria. Modern dental practice has adopted zirconia abutments in place o...

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Autores principales: Zühlke, Alexandra, Gasik, Michael, Shahramian, Khalil, Närhi, Timo, Bilotsky, Yevgen, Kangasniemi, Ilkka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832313/
https://www.ncbi.nlm.nih.gov/pubmed/33477782
http://dx.doi.org/10.3390/ma14020455
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author Zühlke, Alexandra
Gasik, Michael
Shahramian, Khalil
Närhi, Timo
Bilotsky, Yevgen
Kangasniemi, Ilkka
author_facet Zühlke, Alexandra
Gasik, Michael
Shahramian, Khalil
Närhi, Timo
Bilotsky, Yevgen
Kangasniemi, Ilkka
author_sort Zühlke, Alexandra
collection PubMed
description Prevention of bacterial inflammation around dental implants (peri-implantitis) is one of the keys to success of the implantation and can be achieved by securing the gingival tissue-abutment interface preventing penetration of bacteria. Modern dental practice has adopted zirconia abutments in place of titanium, but the adhesion of gingival tissue to zirconia is inferior to titanium. The aim of this study was to assess and improve the adhesion of mucosal tissues to zirconia posts using sol-gel derived TiO(2) coating following dynamic mechanical testing. The posts were cultivated with porcine bone-gingival tissue specimens in vitro for 7 and 14 days and then subjected to dynamic mechanical analysis simulating physiological loading at 1 Hz up to 50 μm amplitude. In parallel in silico analysis of stresses and strains have been made simulating “the worst case” when the fixture fails in osseointegration while the abutment still holds. Results show treatment of zirconia can lead to double interface stiffness (static shear stiffness values from 5–10 to 17–23 kPa and dynamic from 20–50 to 60–125 kPa), invariant viscostiffness (from 5–35 to 45–90 kPa·s(α)) and material memory values (increased from 0.06–0.10 to 0.17–0.25), which is beneficial in preventing bacterial contamination in dental implants. This suggests TiO(2)-coated zirconia abutments may have a significant clinical benefit for prevention of the bacterial contamination.
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spelling pubmed-78323132021-01-26 Enhancement of Gingival Tissue Adherence of Zirconia Implant Posts: In Vitro Study Zühlke, Alexandra Gasik, Michael Shahramian, Khalil Närhi, Timo Bilotsky, Yevgen Kangasniemi, Ilkka Materials (Basel) Article Prevention of bacterial inflammation around dental implants (peri-implantitis) is one of the keys to success of the implantation and can be achieved by securing the gingival tissue-abutment interface preventing penetration of bacteria. Modern dental practice has adopted zirconia abutments in place of titanium, but the adhesion of gingival tissue to zirconia is inferior to titanium. The aim of this study was to assess and improve the adhesion of mucosal tissues to zirconia posts using sol-gel derived TiO(2) coating following dynamic mechanical testing. The posts were cultivated with porcine bone-gingival tissue specimens in vitro for 7 and 14 days and then subjected to dynamic mechanical analysis simulating physiological loading at 1 Hz up to 50 μm amplitude. In parallel in silico analysis of stresses and strains have been made simulating “the worst case” when the fixture fails in osseointegration while the abutment still holds. Results show treatment of zirconia can lead to double interface stiffness (static shear stiffness values from 5–10 to 17–23 kPa and dynamic from 20–50 to 60–125 kPa), invariant viscostiffness (from 5–35 to 45–90 kPa·s(α)) and material memory values (increased from 0.06–0.10 to 0.17–0.25), which is beneficial in preventing bacterial contamination in dental implants. This suggests TiO(2)-coated zirconia abutments may have a significant clinical benefit for prevention of the bacterial contamination. MDPI 2021-01-19 /pmc/articles/PMC7832313/ /pubmed/33477782 http://dx.doi.org/10.3390/ma14020455 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zühlke, Alexandra
Gasik, Michael
Shahramian, Khalil
Närhi, Timo
Bilotsky, Yevgen
Kangasniemi, Ilkka
Enhancement of Gingival Tissue Adherence of Zirconia Implant Posts: In Vitro Study
title Enhancement of Gingival Tissue Adherence of Zirconia Implant Posts: In Vitro Study
title_full Enhancement of Gingival Tissue Adherence of Zirconia Implant Posts: In Vitro Study
title_fullStr Enhancement of Gingival Tissue Adherence of Zirconia Implant Posts: In Vitro Study
title_full_unstemmed Enhancement of Gingival Tissue Adherence of Zirconia Implant Posts: In Vitro Study
title_short Enhancement of Gingival Tissue Adherence of Zirconia Implant Posts: In Vitro Study
title_sort enhancement of gingival tissue adherence of zirconia implant posts: in vitro study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832313/
https://www.ncbi.nlm.nih.gov/pubmed/33477782
http://dx.doi.org/10.3390/ma14020455
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