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FDA recommended potent drugs against COVID-19: Insight through molecular docking

Human Coronavirus (COVID-19) is a worldwide pandemic of 2019–20 that was emerged in China in December 2019. More than 37,000deaths with7, 84, 440confirmed cases has been reported from around 200 different countries has been reported till now and the number is increasing every second. The spread is s...

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Detalles Bibliográficos
Autores principales: Gumber, Khushbu, Pomila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832574/
https://www.ncbi.nlm.nih.gov/pubmed/33520672
http://dx.doi.org/10.1016/j.matpr.2020.12.649
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author Gumber, Khushbu
Pomila
author_facet Gumber, Khushbu
Pomila
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description Human Coronavirus (COVID-19) is a worldwide pandemic of 2019–20 that was emerged in China in December 2019. More than 37,000deaths with7, 84, 440confirmed cases has been reported from around 200 different countries has been reported till now and the number is increasing every second. The spread is said to be through human to human transmission via close contact or respiratory droplets produced when people cough or sneeze. No treatment for the illness has been approved yet. The urgent need is to find solution to this growing problem that has affected the whole mankind. World Health Organisation (WHO) as well as US Food and Drug Administration (FDA) are continuously working to find the solution. In the same line they have proposed many potent drugs that may have efficiency against the newly emerged viral infection. To support the efforts the present study is designed to carry out the in silico analysis viz. Docking studies of around 16drugs recently recommended by US FDA by observing the interaction of test molecules with SARS proteinase.
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spelling pubmed-78325742021-01-26 FDA recommended potent drugs against COVID-19: Insight through molecular docking Gumber, Khushbu Pomila Mater Today Proc Article Human Coronavirus (COVID-19) is a worldwide pandemic of 2019–20 that was emerged in China in December 2019. More than 37,000deaths with7, 84, 440confirmed cases has been reported from around 200 different countries has been reported till now and the number is increasing every second. The spread is said to be through human to human transmission via close contact or respiratory droplets produced when people cough or sneeze. No treatment for the illness has been approved yet. The urgent need is to find solution to this growing problem that has affected the whole mankind. World Health Organisation (WHO) as well as US Food and Drug Administration (FDA) are continuously working to find the solution. In the same line they have proposed many potent drugs that may have efficiency against the newly emerged viral infection. To support the efforts the present study is designed to carry out the in silico analysis viz. Docking studies of around 16drugs recently recommended by US FDA by observing the interaction of test molecules with SARS proteinase. Elsevier Ltd. 2021 2021-01-13 /pmc/articles/PMC7832574/ /pubmed/33520672 http://dx.doi.org/10.1016/j.matpr.2020.12.649 Text en © 2021 Elsevier Ltd. All rights reserved. Selection and peer-review under responsibility of the scientific committee of the International Conference on Advances in Materials Research ? 2019. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Gumber, Khushbu
Pomila
FDA recommended potent drugs against COVID-19: Insight through molecular docking
title FDA recommended potent drugs against COVID-19: Insight through molecular docking
title_full FDA recommended potent drugs against COVID-19: Insight through molecular docking
title_fullStr FDA recommended potent drugs against COVID-19: Insight through molecular docking
title_full_unstemmed FDA recommended potent drugs against COVID-19: Insight through molecular docking
title_short FDA recommended potent drugs against COVID-19: Insight through molecular docking
title_sort fda recommended potent drugs against covid-19: insight through molecular docking
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832574/
https://www.ncbi.nlm.nih.gov/pubmed/33520672
http://dx.doi.org/10.1016/j.matpr.2020.12.649
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