Are the emerging SARS-COV-2 mutations friend or foe?

• Current two important SARS-CoV-2 variants are D614 G and N501Y. • They cause S1 of the spike protein to open conformation. • Open conformation may increase the transmissibility of the virus. • Open conformation may also increase the immunogenicity of the S1 epitopes.

Detalles Bibliográficos
Autor principal: Erol, Adnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Federation of Immunological Societies. Published by Elsevier B.V. 2021
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832648/
https://www.ncbi.nlm.nih.gov/pubmed/33400966
http://dx.doi.org/10.1016/j.imlet.2020.12.014
_version_ 1783641883320254464
author Erol, Adnan
author_facet Erol, Adnan
author_sort Erol, Adnan
collection PubMed
description • Current two important SARS-CoV-2 variants are D614 G and N501Y. • They cause S1 of the spike protein to open conformation. • Open conformation may increase the transmissibility of the virus. • Open conformation may also increase the immunogenicity of the S1 epitopes.
format Online
Article
Text
id pubmed-7832648
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher European Federation of Immunological Societies. Published by Elsevier B.V.
record_format MEDLINE/PubMed
spelling pubmed-78326482021-01-26 Are the emerging SARS-COV-2 mutations friend or foe? Erol, Adnan Immunol Lett Correspondence • Current two important SARS-CoV-2 variants are D614 G and N501Y. • They cause S1 of the spike protein to open conformation. • Open conformation may increase the transmissibility of the virus. • Open conformation may also increase the immunogenicity of the S1 epitopes. European Federation of Immunological Societies. Published by Elsevier B.V. 2021-02 2021-01-02 /pmc/articles/PMC7832648/ /pubmed/33400966 http://dx.doi.org/10.1016/j.imlet.2020.12.014 Text en © 2021 European Federation of Immunological Societies. Published by Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Correspondence
Erol, Adnan
Are the emerging SARS-COV-2 mutations friend or foe?
title Are the emerging SARS-COV-2 mutations friend or foe?
title_full Are the emerging SARS-COV-2 mutations friend or foe?
title_fullStr Are the emerging SARS-COV-2 mutations friend or foe?
title_full_unstemmed Are the emerging SARS-COV-2 mutations friend or foe?
title_short Are the emerging SARS-COV-2 mutations friend or foe?
title_sort are the emerging sars-cov-2 mutations friend or foe?
topic Correspondence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832648/
https://www.ncbi.nlm.nih.gov/pubmed/33400966
http://dx.doi.org/10.1016/j.imlet.2020.12.014
work_keys_str_mv AT eroladnan aretheemergingsarscov2mutationsfriendorfoe

Ejemplares similares