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Orai1 Channels Are Essential for Amplification of Glutamate-Evoked Ca(2+) Signals in Dendritic Spines to Regulate Working and Associative Memory

Store-operated Orai1 calcium channels function as highly Ca(2+)-selective ion channels and are broadly expressed in many tissues including the central nervous system, but their contributions to cognitive processing are largely unknown. Here, we report that many measures of synaptic, cellular, and be...

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Detalles Bibliográficos
Autores principales: Maneshi, Mohammad Mehdi, Toth, Anna B., Ishii, Toshiyuki, Hori, Kotaro, Tsujikawa, Shogo, Shum, Andrew K., Shrestha, Nisha, Yamashita, Megumi, Miller, Richard J., Radulovic, Jelena, Swanson, Geoffrey T., Prakriya, Murali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832685/
https://www.ncbi.nlm.nih.gov/pubmed/33264616
http://dx.doi.org/10.1016/j.celrep.2020.108464