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Use of capnography to verify emergency ventilator sharing in the COVID-19 era

Exacerbation of COVID-19 pandemic may lead to acute shortage of ventilators, which may require shared use of ventilator as a lifesaving concept. Two model lungs were ventilated with one ventilator to i) test the adequacy of individual tidal volumes via capnography, ii) assess cross-breathing between...

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Autores principales: Korsós, Anita, Peták, Ferenc, Südy, Roberta, Schranc, Álmos, Fodor, Gergely H., Babik, Barna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832691/
https://www.ncbi.nlm.nih.gov/pubmed/33359758
http://dx.doi.org/10.1016/j.resp.2020.103611
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author Korsós, Anita
Peták, Ferenc
Südy, Roberta
Schranc, Álmos
Fodor, Gergely H.
Babik, Barna
author_facet Korsós, Anita
Peták, Ferenc
Südy, Roberta
Schranc, Álmos
Fodor, Gergely H.
Babik, Barna
author_sort Korsós, Anita
collection PubMed
description Exacerbation of COVID-19 pandemic may lead to acute shortage of ventilators, which may require shared use of ventilator as a lifesaving concept. Two model lungs were ventilated with one ventilator to i) test the adequacy of individual tidal volumes via capnography, ii) assess cross-breathing between lungs, and iii) offer a simulation-based algorithm for ensuring equal tidal volumes. Ventilation asymmetry was induced by placing rubber band around one model lung, and the uneven distribution of tidal volumes (VT) was counterbalanced by elevating airflow resistance (HR) contralaterally. VT, end-tidal CO(2) concentration (ETCO(2)), and peak inspiratory pressure (Ppi) were measured. Unilateral LC reduced VT and elevated ETCO(2) on the affected side. Under HR, VT and ETCO(2) were re-equilibrated. In conclusion, capnography serves as simple, bedside method for controlling the adequacy of split ventilation in each patient. No collateral gas flow was observed between the two lungs with different time constants. Ventilator sharing may play a role in emergency situations.
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spelling pubmed-78326912021-01-26 Use of capnography to verify emergency ventilator sharing in the COVID-19 era Korsós, Anita Peták, Ferenc Südy, Roberta Schranc, Álmos Fodor, Gergely H. Babik, Barna Respir Physiol Neurobiol Article Exacerbation of COVID-19 pandemic may lead to acute shortage of ventilators, which may require shared use of ventilator as a lifesaving concept. Two model lungs were ventilated with one ventilator to i) test the adequacy of individual tidal volumes via capnography, ii) assess cross-breathing between lungs, and iii) offer a simulation-based algorithm for ensuring equal tidal volumes. Ventilation asymmetry was induced by placing rubber band around one model lung, and the uneven distribution of tidal volumes (VT) was counterbalanced by elevating airflow resistance (HR) contralaterally. VT, end-tidal CO(2) concentration (ETCO(2)), and peak inspiratory pressure (Ppi) were measured. Unilateral LC reduced VT and elevated ETCO(2) on the affected side. Under HR, VT and ETCO(2) were re-equilibrated. In conclusion, capnography serves as simple, bedside method for controlling the adequacy of split ventilation in each patient. No collateral gas flow was observed between the two lungs with different time constants. Ventilator sharing may play a role in emergency situations. Elsevier B.V. 2021-03 2020-12-24 /pmc/articles/PMC7832691/ /pubmed/33359758 http://dx.doi.org/10.1016/j.resp.2020.103611 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Korsós, Anita
Peták, Ferenc
Südy, Roberta
Schranc, Álmos
Fodor, Gergely H.
Babik, Barna
Use of capnography to verify emergency ventilator sharing in the COVID-19 era
title Use of capnography to verify emergency ventilator sharing in the COVID-19 era
title_full Use of capnography to verify emergency ventilator sharing in the COVID-19 era
title_fullStr Use of capnography to verify emergency ventilator sharing in the COVID-19 era
title_full_unstemmed Use of capnography to verify emergency ventilator sharing in the COVID-19 era
title_short Use of capnography to verify emergency ventilator sharing in the COVID-19 era
title_sort use of capnography to verify emergency ventilator sharing in the covid-19 era
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7832691/
https://www.ncbi.nlm.nih.gov/pubmed/33359758
http://dx.doi.org/10.1016/j.resp.2020.103611
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