Cargando…

De Novo Profiling of Long Non-Coding RNAs Involved in MC-LR-Induced Liver Injury in Whitefish: Discovery and Perspectives

Microcystin-LR (MC-LR) is a potent hepatotoxin for which a substantial gap in knowledge persists regarding the underlying molecular mechanisms of liver toxicity and injury. Although long non-coding RNAs (lncRNAs) have been extensively studied in model organisms, our knowledge concerning the role of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Florczyk, Maciej, Brzuzan, Paweł, Woźny, Maciej
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833382/ https://www.ncbi.nlm.nih.gov/pubmed/33477898 http://dx.doi.org/10.3390/ijms22020941

Ejemplares similares

Illumina Sequencing Reveals Aberrant Expression of MicroRNAs and Their Variants in Whitefish (Coregonus lavaretus) Liver after Exposure to Microcystin-LR
por: Brzuzan, Paweł, et al.
Publicado: (2016)

Microcystin-LR-Triggered Neuronal Toxicity in Whitefish Does Not Involve MiR124-3p
por: Florczyk, Maciej, et al.
Publicado: (2018)

Microcystin-LR (MC-LR) Triggers Inflammatory Responses in Macrophages
por: Su, Robin C., et al.
Publicado: (2021)

Splice-acceptor site mutation in p53 gene of hu888 zebrafish line
por: Piasecka, Alicja, et al.
Publicado: (2014)

MiR92b-3p synthetic analogue impairs zebrafish embryonic development, leading to ocular defects, decreased movement and hatching rate, and increased mortality
por: Kranert, Kilian, et al.
Publicado: (2022)

Author Correction: Domestication process modifies digestion ability in larvae of Eurasian perch (Perca fluviatilis), a freshwater Teleostei
por: Palińska-Żarska, Katarzyna, et al.
Publicado: (2020)

Domestication process modifies digestion ability in larvae of Eurasian perch (Perca fluviatilis), a freshwater Teleostei
por: Palińska-Żarska, Katarzyna, et al.
Publicado: (2020)

The Influence of Zearalenone on Selected Hemostatic Parameters in Sexually Immature Gilts
por: Jakimiuk, Ewa, et al.
Publicado: (2021)

Biological Activity and Stability of Aeruginosamides from Cyanobacteria
por: Cegłowska, Marta, et al.
Publicado: (2022)

[D-Leu(1)]MC-LR Has Lower PP1 Inhibitory Capability and Greater Toxic Potency than MC-LR in Animal and Plant Tissues
por: Sedan, Daniela, et al.
Publicado: (2020)

Analysis of MicroRNA Expression Profiling Involved in MC-LR-Induced Cytotoxicity by High-Throughput Sequencing
por: Ma, Junguo, et al.
Publicado: (2017)

Regulatory versus coding signatures of natural selection in a candidate gene involved in the adaptive divergence of whitefish species pairs (Coregonus spp.)
por: Jeukens, Julie, et al.
Publicado: (2012)

Influence of deoxynivalenol and zearalenone on the immunohistochemical expression of oestrogen receptors and liver enzyme genes in vivo in prepubertal gilts
por: Gajęcka, Magdalena, et al.
Publicado: (2023)

CD40 Receptor Knockout Protects against Microcystin-LR (MC-LR) Prolongation and Exacerbation of Dextran Sulfate Sodium (DSS)-Induced Colitis
por: Su, Robin C., et al.
Publicado: (2020)

Cardiac Toxicity Induced by Long-Term Environmental Levels of MC-LR Exposure in Mice
por: Yan, Canqun, et al.
Publicado: (2023)

Exposure to the Harmful Algal Bloom (HAB) Toxin Microcystin-LR (MC-LR) Prolongs and Increases Severity of Dextran Sulfate Sodium (DSS)-Induced Colitis
por: Su, Robin C., et al.
Publicado: (2019)

A de novo chromosome‐level genome assembly of Coregonus sp. “Balchen”: One representative of the Swiss Alpine whitefish radiation
por: De‐Kayne, Rishi, et al.
Publicado: (2020)

Rapid buildup of sympatric species diversity in Alpine whitefish
por: Doenz, Carmela J., et al.
Publicado: (2018)

Genomic architecture of adaptive radiation and hybridization in Alpine whitefish
por: De-Kayne, Rishi, et al.
Publicado: (2022)

MC-LR Exposure Leads to Subfertility of Female Mice and Induces Oxidative Stress in Granulosa Cells
por: Wu, Jiang, et al.
Publicado: (2015)

Phytoremediation of CYN, MC-LR and ANTX-a from Water by the Submerged Macrophyte Lemna trisulca
por: Kucała, Małgorzata, et al.
Publicado: (2021)

Discovery of long non-coding RNAs in the liver fluke, Fasciola hepatica
por: McVeigh, Paul, et al.
Publicado: (2023)

Microcystin-LR in Primary Liver Cancers: An Overview
por: Gu, Shen, et al.
Publicado: (2022)

[D-Leu(1)]MC-LR and MC-LR: A Small–Large Difference: Significantly Different Effects on Phaseolus vulgaris L. (Fabaceae) Growth and Phototropic Response after Single Contact during Imbibition with Each of These Microcystin Variants
por: Malaissi, Luciano, et al.
Publicado: (2020)

Nitrite Enhances MC-LR-Induced Changes on Splenic Oxidation Resistance and Innate Immunity in Male Zebrafish
por: Lin, Wang, et al.
Publicado: (2018)

TIME-TEMPERATURE RELATIONS IN THE INCUBATION OF THE WHITEFISH, COREGONUS CLUPEAFORMIS (MITCHILL)
por: Price, John W.
Publicado: (1940)

Using mathematical modelling to investigate the adaptive divergence of whitefish in Fennoscandia
por: Thibert-Plante, Xavier, et al.
Publicado: (2020)

Deep learning LI-RADS grading system based on contrast enhanced multiphase MRI for differentiation between LR-3 and LR-4/LR-5 liver tumors
por: Wu, Yunan, et al.
Publicado: (2020)

Beyond the proteome: non-coding regulatory RNAs
por: Szymański, Maciej, et al.
Publicado: (2002)

The Abnormal Proliferation of Hepatocytes is Associated with MC-LR and C-Terminal Truncated HBX Synergistic Disturbance of the Redox Balance
por: Cai, Dong-Mei, et al.
Publicado: (2022)

Genomic signatures of relaxed disruptive selection associated with speciation reversal in whitefish
por: Hudson, Alan G, et al.
Publicado: (2013)

Holobionts and ecological speciation: the intestinal microbiota of lake whitefish species pairs
por: Sevellec, Maelle, et al.
Publicado: (2018)

Size‐selective fishing and the potential for fisheries‐induced evolution in lake whitefish
por: Morbey, Yolanda E., et al.
Publicado: (2018)

Ecological speciation in European whitefish is driven by a large‐gaped predator
por: Öhlund, Gunnar, et al.
Publicado: (2020)

Identification of Candidate Genes and Physiological Pathways Involved in Gonad Deformation in Whitefish (Coregonus spp.) from Lake Thun, Switzerland
por: Bittner, David, et al.
Publicado: (2011)

Interaction Effects of AFB1 and MC-LR Co-exposure with Polymorphism of Metabolic Genes on Liver Damage: focusing on SLCO1B1 and GSTP1
por: Yang, Xiaohong, et al.
Publicado: (2017)

Degradation of [Dha(7)]MC-LR by a Microcystin Degrading Bacterium Isolated from Lake Rotoiti, New Zealand
por: Somdee, Theerasak, et al.
Publicado: (2013)

Liver Diseases and Long Non-Coding RNAs: New Insight and Perspective
por: Quagliata, Luca, et al.
Publicado: (2014)

Speciation Reversal in European Whitefish (Coregonus lavaretus (L.)) Caused by Competitor Invasion
por: Bhat, Shripathi, et al.
Publicado: (2014)

Thermal experience during embryogenesis contributes to the induction of dwarfism in whitefish Coregonus lavaretus
por: Steinbacher, Peter, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_p6jddrgkc8ijp0onpbgs0tqc0p