Combined Effects of Methylated Cytosine and Molecular Crowding on the Thermodynamic Stability of DNA Duplexes

Methylated cytosine within CpG dinucleotides is a key factor for epigenetic gene regulation. It has been revealed that methylated cytosine decreases DNA backbone flexibility and increases the thermal stability of DNA. Although the molecular environment is an important factor for the structure, therm...

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Detalles Bibliográficos
Autores principales: Tsuruta, Mitsuki, Sugitani, Yui, Sugimoto, Naoki, Miyoshi, Daisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833394/
https://www.ncbi.nlm.nih.gov/pubmed/33477917
http://dx.doi.org/10.3390/ijms22020947

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833394/
https://www.ncbi.nlm.nih.gov/pubmed/33477917
http://dx.doi.org/10.3390/ijms22020947

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