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Extracellular Prolidase (PEPD) Induces Anabolic Processes through EGFR, β(1)-integrin, and IGF-1R Signaling Pathways in an Experimental Model of Wounded Fibroblasts

The role of prolidase (PEPD) as a ligand of the epidermal growth factor receptor (EGFR) was studied in an experimental model of wound healing in cultured fibroblasts. The cells were treated with PEPD (1–100 nM) and analysis of cell viability, proliferation, migration, collagen biosynthesis, PEPD act...

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Detalles Bibliográficos
Autores principales: Baszanowska, Weronika, Misiura, Magdalena, Oscilowska, Ilona, Palka, Jerzy, Miltyk, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833428/
https://www.ncbi.nlm.nih.gov/pubmed/33477899
http://dx.doi.org/10.3390/ijms22020942

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