Thermovaccination – thermoheliox as a stimulator of the immune response. Kinetics of the synthesis of antibodies and C-reactive protein in coronavirus infection

Clinical trials of thermoheliox application (inhalation with a high-temperature mixture of oxygen and helium, 90 °C) in the treatment of the acute phase of coronavirus infection were conducted. Dynamics of disease development in infected patients (PCR test for the virus) and, dynamics of changes in...

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Autores principales: Varfolomeev, Sergey D., Panin, Alexander A., Bykov, Valeriy I., Tsybenova, Svetlana B., Zhuravel, Sergey V., Ryabokon, Anna M., Utkina, Irina I., Gavrilov, Pavel V., Petrikov, Sergey S., Shogenova, Lyudmila V., Chuchalin, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833474/
https://www.ncbi.nlm.nih.gov/pubmed/33316227
http://dx.doi.org/10.1016/j.cbi.2020.109339
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author Varfolomeev, Sergey D.
Panin, Alexander A.
Bykov, Valeriy I.
Tsybenova, Svetlana B.
Zhuravel, Sergey V.
Ryabokon, Anna M.
Utkina, Irina I.
Gavrilov, Pavel V.
Petrikov, Sergey S.
Shogenova, Lyudmila V.
Chuchalin, Alexander G.
author_facet Varfolomeev, Sergey D.
Panin, Alexander A.
Bykov, Valeriy I.
Tsybenova, Svetlana B.
Zhuravel, Sergey V.
Ryabokon, Anna M.
Utkina, Irina I.
Gavrilov, Pavel V.
Petrikov, Sergey S.
Shogenova, Lyudmila V.
Chuchalin, Alexander G.
author_sort Varfolomeev, Sergey D.
collection PubMed
description Clinical trials of thermoheliox application (inhalation with a high-temperature mixture of oxygen and helium, 90 °C) in the treatment of the acute phase of coronavirus infection were conducted. Dynamics of disease development in infected patients (PCR test for the virus) and, dynamics of changes in blood concentration of C-reactive protein, immunoglobulin M, specific immunoglobulin G were studied. High efficiency of thermoheliox in releasing the organism from the virus and stimulating the immune response (thermovaccination effect) was shown. The kinetic model of the process is proposed and analyzed.
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spelling pubmed-78334742021-01-26 Thermovaccination – thermoheliox as a stimulator of the immune response. Kinetics of the synthesis of antibodies and C-reactive protein in coronavirus infection Varfolomeev, Sergey D. Panin, Alexander A. Bykov, Valeriy I. Tsybenova, Svetlana B. Zhuravel, Sergey V. Ryabokon, Anna M. Utkina, Irina I. Gavrilov, Pavel V. Petrikov, Sergey S. Shogenova, Lyudmila V. Chuchalin, Alexander G. Chem Biol Interact Article Clinical trials of thermoheliox application (inhalation with a high-temperature mixture of oxygen and helium, 90 °C) in the treatment of the acute phase of coronavirus infection were conducted. Dynamics of disease development in infected patients (PCR test for the virus) and, dynamics of changes in blood concentration of C-reactive protein, immunoglobulin M, specific immunoglobulin G were studied. High efficiency of thermoheliox in releasing the organism from the virus and stimulating the immune response (thermovaccination effect) was shown. The kinetic model of the process is proposed and analyzed. Elsevier B.V. 2021-01-25 2020-12-11 /pmc/articles/PMC7833474/ /pubmed/33316227 http://dx.doi.org/10.1016/j.cbi.2020.109339 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Varfolomeev, Sergey D.
Panin, Alexander A.
Bykov, Valeriy I.
Tsybenova, Svetlana B.
Zhuravel, Sergey V.
Ryabokon, Anna M.
Utkina, Irina I.
Gavrilov, Pavel V.
Petrikov, Sergey S.
Shogenova, Lyudmila V.
Chuchalin, Alexander G.
Thermovaccination – thermoheliox as a stimulator of the immune response. Kinetics of the synthesis of antibodies and C-reactive protein in coronavirus infection
title Thermovaccination – thermoheliox as a stimulator of the immune response. Kinetics of the synthesis of antibodies and C-reactive protein in coronavirus infection
title_full Thermovaccination – thermoheliox as a stimulator of the immune response. Kinetics of the synthesis of antibodies and C-reactive protein in coronavirus infection
title_fullStr Thermovaccination – thermoheliox as a stimulator of the immune response. Kinetics of the synthesis of antibodies and C-reactive protein in coronavirus infection
title_full_unstemmed Thermovaccination – thermoheliox as a stimulator of the immune response. Kinetics of the synthesis of antibodies and C-reactive protein in coronavirus infection
title_short Thermovaccination – thermoheliox as a stimulator of the immune response. Kinetics of the synthesis of antibodies and C-reactive protein in coronavirus infection
title_sort thermovaccination – thermoheliox as a stimulator of the immune response. kinetics of the synthesis of antibodies and c-reactive protein in coronavirus infection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833474/
https://www.ncbi.nlm.nih.gov/pubmed/33316227
http://dx.doi.org/10.1016/j.cbi.2020.109339
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