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Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials

[Image: see text] Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable) protecting groups (PPGs), also known as caged or photocaged compounds, are used to enable non-invasive spatiotemporal photochemical control over the release of species of interest. Recent years hav...

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Autores principales: Weinstain, Roy, Slanina, Tomáš, Kand, Dnyaneshwar, Klán, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833475/
https://www.ncbi.nlm.nih.gov/pubmed/33125209
http://dx.doi.org/10.1021/acs.chemrev.0c00663
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author Weinstain, Roy
Slanina, Tomáš
Kand, Dnyaneshwar
Klán, Petr
author_facet Weinstain, Roy
Slanina, Tomáš
Kand, Dnyaneshwar
Klán, Petr
author_sort Weinstain, Roy
collection PubMed
description [Image: see text] Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable) protecting groups (PPGs), also known as caged or photocaged compounds, are used to enable non-invasive spatiotemporal photochemical control over the release of species of interest. Recent years have seen the development of PPGs activatable by biologically and chemically benign visible and near-infrared (NIR) light. These long-wavelength-absorbing moieties expand the applicability of this powerful method and its accessibility to non-specialist users. This review comprehensively covers organic and transition metal-containing photoactivatable compounds (complexes) that absorb in the visible- and NIR-range to release various leaving groups and gasotransmitters (carbon monoxide, nitric oxide, and hydrogen sulfide). The text also covers visible- and NIR-light-induced photosensitized release using molecular sensitizers, quantum dots, and upconversion and second-harmonic nanoparticles, as well as release via photodynamic (photooxygenation by singlet oxygen) and photothermal effects. Release from photoactivatable polymers, micelles, vesicles, and photoswitches, along with the related emerging field of photopharmacology, is discussed at the end of the review.
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spelling pubmed-78334752021-01-26 Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials Weinstain, Roy Slanina, Tomáš Kand, Dnyaneshwar Klán, Petr Chem Rev [Image: see text] Photoactivatable (alternatively, photoremovable, photoreleasable, or photocleavable) protecting groups (PPGs), also known as caged or photocaged compounds, are used to enable non-invasive spatiotemporal photochemical control over the release of species of interest. Recent years have seen the development of PPGs activatable by biologically and chemically benign visible and near-infrared (NIR) light. These long-wavelength-absorbing moieties expand the applicability of this powerful method and its accessibility to non-specialist users. This review comprehensively covers organic and transition metal-containing photoactivatable compounds (complexes) that absorb in the visible- and NIR-range to release various leaving groups and gasotransmitters (carbon monoxide, nitric oxide, and hydrogen sulfide). The text also covers visible- and NIR-light-induced photosensitized release using molecular sensitizers, quantum dots, and upconversion and second-harmonic nanoparticles, as well as release via photodynamic (photooxygenation by singlet oxygen) and photothermal effects. Release from photoactivatable polymers, micelles, vesicles, and photoswitches, along with the related emerging field of photopharmacology, is discussed at the end of the review. American Chemical Society 2020-10-30 2020-12-23 /pmc/articles/PMC7833475/ /pubmed/33125209 http://dx.doi.org/10.1021/acs.chemrev.0c00663 Text en © 2020 American Chemical Society This is an open access article published under a Creative Commons Non-Commercial No Derivative Works (CC-BY-NC-ND) Attribution License (http://pubs.acs.org/page/policy/authorchoice_ccbyncnd_termsofuse.html) , which permits copying and redistribution of the article, and creation of adaptations, all for non-commercial purposes.
spellingShingle Weinstain, Roy
Slanina, Tomáš
Kand, Dnyaneshwar
Klán, Petr
Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials
title Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials
title_full Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials
title_fullStr Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials
title_full_unstemmed Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials
title_short Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials
title_sort visible-to-nir-light activated release: from small molecules to nanomaterials
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833475/
https://www.ncbi.nlm.nih.gov/pubmed/33125209
http://dx.doi.org/10.1021/acs.chemrev.0c00663
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