Sex- or Gender-specific Differences in the Clinical Presentation, Outcome, and Treatment of SARS-CoV-2

This review describes the sex and gender differences in COVID-19 presentation, treatment, and outcomes. We discuss the differences between the sexes in susceptibility to infection, the role of sex chromosomes on the body's immunologic response and the influence of hormones on the body's re...

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Detalles Bibliográficos
Autores principales: Wolfe, Jeannette, Safdar, Basmah, Madsen, Tracy E., Sethuraman, Kinjal N., Becker, Bruce, Greenberg, Marna Rayl, McGregor, Alyson J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
COVID Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833665/
https://www.ncbi.nlm.nih.gov/pubmed/33583576
http://dx.doi.org/10.1016/j.clinthera.2021.01.015
Descripción
Sumario:This review describes the sex and gender differences in COVID-19 presentation, treatment, and outcomes. We discuss the differences between the sexes in susceptibility to infection, the role of sex chromosomes on the body's immunologic response and the influence of hormones on the body's response to the virus. Additionally, the sex differences in clinical and laboratory presentation, complications of infection and outcomes, as well as differences in response to treatment and prevention are reviewed.

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