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A cross-sectional seroprevalence for COVID-19 among healthcare workers in a tertially care hospital in Taiwan

BACKGROUND: Healthcare workers (HCWs) are at the frontline during the pandemic of COVID-19 globally. According to the WHO situation report at April 17, there were 22, 073 HCWs contracted the infection. Whether the infection control policy and practice in the hospital setting can protect the HCWs is...

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Autores principales: Pan, Sung-Ching, Huang, Yu-Shan, Hsieh, Szu-Min, Chen, Yee-Chun, Chang, Sui-Yuan, Chang, Shan-Chwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Formosan Medical Association. Published by Elsevier Taiwan LLC. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833685/
https://www.ncbi.nlm.nih.gov/pubmed/33461841
http://dx.doi.org/10.1016/j.jfma.2021.01.002
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author Pan, Sung-Ching
Huang, Yu-Shan
Hsieh, Szu-Min
Chen, Yee-Chun
Chang, Sui-Yuan
Chang, Shan-Chwen
author_facet Pan, Sung-Ching
Huang, Yu-Shan
Hsieh, Szu-Min
Chen, Yee-Chun
Chang, Sui-Yuan
Chang, Shan-Chwen
author_sort Pan, Sung-Ching
collection PubMed
description BACKGROUND: Healthcare workers (HCWs) are at the frontline during the pandemic of COVID-19 globally. According to the WHO situation report at April 17, there were 22, 073 HCWs contracted the infection. Whether the infection control policy and practice in the hospital setting can protect the HCWs is an important issue. METHODS: We performed a cross-sectional serology study in a tertiary care hospital in Taiwan to explore the sero-prevalence rate among HCWs. The participants are enrolled on a voluntary basis. A structured questionnaire was collected to gather the epidemiology character and risk factors for potential exposure. ELISA tests as Architect SARS-CoV-2 IgG (Abbott) and Elecsys Anti-SARS-CoV-2 assay (Roche) were used to detect antibody responses. If any of the tests was positive, a western blot assay was used for confirmation. RESULTS: There were 194 HCWs participated during July 1 to Aug. 31, 2020. The mean age was 36.3 ± 10.4. More than half of the participants had possible hospital associated risk for COVID-19 exposure (110/192, 57.3%) and 64 had possible community risk for COVID-19 exposure (64/194, 33.0%). There was only one participant had positive test by Architect IgG test and confirmed to be negative for seasonal coronavirus and SARS-CoV-2 antibody. (Mikrogen Diagnostik, Germany). CONCLUSION: The cross-sectional serology study in a tertiary care hospital in Taiwan revealed no HCWs had positive serology response to SARS-CoV-2. We believe that the infection control policy and practice in the hospital and in the community are both important to prevent the disease transmission.
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spelling pubmed-78336852021-01-26 A cross-sectional seroprevalence for COVID-19 among healthcare workers in a tertially care hospital in Taiwan Pan, Sung-Ching Huang, Yu-Shan Hsieh, Szu-Min Chen, Yee-Chun Chang, Sui-Yuan Chang, Shan-Chwen J Formos Med Assoc Original Article BACKGROUND: Healthcare workers (HCWs) are at the frontline during the pandemic of COVID-19 globally. According to the WHO situation report at April 17, there were 22, 073 HCWs contracted the infection. Whether the infection control policy and practice in the hospital setting can protect the HCWs is an important issue. METHODS: We performed a cross-sectional serology study in a tertiary care hospital in Taiwan to explore the sero-prevalence rate among HCWs. The participants are enrolled on a voluntary basis. A structured questionnaire was collected to gather the epidemiology character and risk factors for potential exposure. ELISA tests as Architect SARS-CoV-2 IgG (Abbott) and Elecsys Anti-SARS-CoV-2 assay (Roche) were used to detect antibody responses. If any of the tests was positive, a western blot assay was used for confirmation. RESULTS: There were 194 HCWs participated during July 1 to Aug. 31, 2020. The mean age was 36.3 ± 10.4. More than half of the participants had possible hospital associated risk for COVID-19 exposure (110/192, 57.3%) and 64 had possible community risk for COVID-19 exposure (64/194, 33.0%). There was only one participant had positive test by Architect IgG test and confirmed to be negative for seasonal coronavirus and SARS-CoV-2 antibody. (Mikrogen Diagnostik, Germany). CONCLUSION: The cross-sectional serology study in a tertiary care hospital in Taiwan revealed no HCWs had positive serology response to SARS-CoV-2. We believe that the infection control policy and practice in the hospital and in the community are both important to prevent the disease transmission. Formosan Medical Association. Published by Elsevier Taiwan LLC. 2021-07 2021-01-09 /pmc/articles/PMC7833685/ /pubmed/33461841 http://dx.doi.org/10.1016/j.jfma.2021.01.002 Text en © 2021 Formosan Medical Association. Published by Elsevier Taiwan LLC. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Original Article
Pan, Sung-Ching
Huang, Yu-Shan
Hsieh, Szu-Min
Chen, Yee-Chun
Chang, Sui-Yuan
Chang, Shan-Chwen
A cross-sectional seroprevalence for COVID-19 among healthcare workers in a tertially care hospital in Taiwan
title A cross-sectional seroprevalence for COVID-19 among healthcare workers in a tertially care hospital in Taiwan
title_full A cross-sectional seroprevalence for COVID-19 among healthcare workers in a tertially care hospital in Taiwan
title_fullStr A cross-sectional seroprevalence for COVID-19 among healthcare workers in a tertially care hospital in Taiwan
title_full_unstemmed A cross-sectional seroprevalence for COVID-19 among healthcare workers in a tertially care hospital in Taiwan
title_short A cross-sectional seroprevalence for COVID-19 among healthcare workers in a tertially care hospital in Taiwan
title_sort cross-sectional seroprevalence for covid-19 among healthcare workers in a tertially care hospital in taiwan
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833685/
https://www.ncbi.nlm.nih.gov/pubmed/33461841
http://dx.doi.org/10.1016/j.jfma.2021.01.002
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