Recombinant tissue plasminogen activator treatment for COVID-19 associated ARDS and acute cor pulmonale

Existing literature highlights the fact that patients with COVID-19 exhibit alterations in the coagulation process and are associated with respiratory and cardiovascular diseases, including acute respiratory distress syndrome and acute cor pulmonale. In this report, we describe the effects of system...

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Detalles Bibliográficos
Autores principales: Kosanovic, Djuro, Yaroshetskiy, Andrey I., Tsareva, Natalia A., Merzhoeva, Zamira M., Trushenko, Natalia V., Nekludova, Galina V., Schermuly, Ralph Theo, Avdeev, Sergey N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833717/
https://www.ncbi.nlm.nih.gov/pubmed/33352323
http://dx.doi.org/10.1016/j.ijid.2020.12.043
Descripción
Sumario:Existing literature highlights the fact that patients with COVID-19 exhibit alterations in the coagulation process and are associated with respiratory and cardiovascular diseases, including acute respiratory distress syndrome and acute cor pulmonale. In this report, we describe the effects of systemic thrombolysis on acute cor pulmonale in a patient suffering from COVID-19. We demonstrated that systemic thrombolysis successfully improved the hemodynamics of our patient and resulted in a prominent reduction in hypercapnia, alveolar dead space, and ventilatory ratio.

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