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Characterization of CD8(+) T-cell responses to non-anchor-type HLA class I neoantigens with single amino-acid substitutions

CD8(+) T cells are capable of recognizing mutation-derived neoantigens displayed by HLA class I molecules, thereby exhibiting the ability to distinguish between cancer and normal cells. However, accumulating evidence has shown that only a small fraction of nonsynonymous somatic mutations give rise t...

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Detalles Bibliográficos
Autores principales:	Shinkawa, Tomoyo, Tokita, Serina, Nakatsugawa, Munehide, Kikuchi, Yasuhiro, Kanaseki, Takayuki, Torigoe, Toshihiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833734/ https://www.ncbi.nlm.nih.gov/pubmed/33537174 http://dx.doi.org/10.1080/2162402X.2020.1870062

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