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Addition of anti-TIM3 or anti-TIGIT Antibodies to anti-PD1 Blockade Augments Human T cell Adoptive Cell Transfer
PD1 blockade to reinvigorate T cells has become part of standard of care for patients with NSCLC across disease stages. However, the majority of patients still do not respond. One potential mechanism of resistance is increased expression of other checkpoint inhibitory molecules on T cells leading to...
Autores principales: | Martinez, Marina, Kim, Soyeon, St. Jean, Naomi, O’Brien, Shaun, Lian, Lurong, Sun, Jing, Verona, Raluca I., Moon, Edmund |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833767/ https://www.ncbi.nlm.nih.gov/pubmed/33537176 http://dx.doi.org/10.1080/2162402X.2021.1873607 |
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