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Assessing the impact of pain-linked Nav1.7 variants: An example of two variants with no biophysical effect

Mutations in the voltage-gated sodium channel Nav1.7 are linked to human pain. The Nav1.7/N1245S variant was described before in several patients suffering from primary erythromelalgia and/or olfactory hypersensitivity. We have identified this variant in a pain patient and a patient suffering from s...

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Detalles Bibliográficos
Autores principales:	Le Cann, Kim, Meents, Jannis E., Sudha Bhagavath Eswaran, Vishal, Dohrn, Maike F., Bott, Raya, Maier, Andrea, Bialer, Martin, Hautvast, Petra, Erickson, Andelain, Rolke, Roman, Rothermel, Markus, Körner, Jannis, Kurth, Ingo, Lampert, Angelika
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833769/ https://www.ncbi.nlm.nih.gov/pubmed/33487118 http://dx.doi.org/10.1080/19336950.2020.1870087

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