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TRPM2 in ischemic stroke: Structure, molecular mechanisms, and drug intervention

Ischemic stroke has a high lethality rate worldwide, and novel treatments are limited. Calcium overload is considered to be one of the mechanisms of cerebral ischemia. Transient receptor potential melastatin 2 (TRPM2) is a reactive oxygen species (ROS)-sensitive calcium channel. Cerebral ischemia-in...

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Detalles Bibliográficos
Autores principales: Wang, Qing, Liu, Ning, Ni, Yuan-Shu, Yang, Jia-Mei, Ma, Lin, Lan, Xiao-Bing, Wu, Jing, Niu, Jian-Guo, Yu, Jian-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7833771/
https://www.ncbi.nlm.nih.gov/pubmed/33455532
http://dx.doi.org/10.1080/19336950.2020.1870088