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Group I p21-activated kinases in leukemia cell adhesion to fibronectin

P21-activated kinases (PAK) regulate processes associated with cytoskeleton dynamics. PAK expression in leukemia cells was measured on protein and mRNA levels. In functional assays, we analyzed the effect of PAK inhibitors IPA-3 and FRAX597 on cell adhesivity and viability. PAK2 was dominant in cell...

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Detalles Bibliográficos
Autores principales:	Kuželová, Kateřina, Obr, Adam, Röselová, Pavla, Grebeňová, Dana, Otevřelová, Petra, Brodská, Barbora, Holoubek, Aleš
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2021
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834095/ https://www.ncbi.nlm.nih.gov/pubmed/33464167 http://dx.doi.org/10.1080/19336918.2021.1872760

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