Importance of hyperglycemia in COVID-19 intensive-care patients: Mechanism and treatment strategy

This review reported that coronavirus disease 2019 (COVID-19) infected patients with short time bed rest or quarantine and airway inflammation are at more risk of developing hyperglycemia and insulin resistance. This condition can induce oxidative stress, decrease immune system function, impair endo...

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Detalles Bibliográficos
Autores principales: Mirzaei, Fatemeh, Khodadadi, Iraj, Vafaei, Seyyed Alireza, Abbasi-Oshaghi, Ebrahim, Tayebinia, Heidar, Farahani, Farhad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Primary Care Diabetes Europe. Published by Elsevier Ltd. 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834268/
https://www.ncbi.nlm.nih.gov/pubmed/33436320
http://dx.doi.org/10.1016/j.pcd.2021.01.002
Descripción
Sumario:This review reported that coronavirus disease 2019 (COVID-19) infected patients with short time bed rest or quarantine and airway inflammation are at more risk of developing hyperglycemia and insulin resistance. This condition can induce oxidative stress, decrease immune system function, impair endothelial function, induce apoptosis, and reduce antioxidant in the lungs. We provide a possible mechanism in severe COVID-19 patients and recommend treatment strategy to reduce mortality rate and prevent adverse outcomes after intensive care unit (ICU).

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