Importance of hyperglycemia in COVID-19 intensive-care patients: Mechanism and treatment strategy

This review reported that coronavirus disease 2019 (COVID-19) infected patients with short time bed rest or quarantine and airway inflammation are at more risk of developing hyperglycemia and insulin resistance. This condition can induce oxidative stress, decrease immune system function, impair endo...

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Autores principales: Mirzaei, Fatemeh, Khodadadi, Iraj, Vafaei, Seyyed Alireza, Abbasi-Oshaghi, Ebrahim, Tayebinia, Heidar, Farahani, Farhad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Primary Care Diabetes Europe. Published by Elsevier Ltd. 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834268/
https://www.ncbi.nlm.nih.gov/pubmed/33436320
http://dx.doi.org/10.1016/j.pcd.2021.01.002
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author Mirzaei, Fatemeh
Khodadadi, Iraj
Vafaei, Seyyed Alireza
Abbasi-Oshaghi, Ebrahim
Tayebinia, Heidar
Farahani, Farhad
author_facet Mirzaei, Fatemeh
Khodadadi, Iraj
Vafaei, Seyyed Alireza
Abbasi-Oshaghi, Ebrahim
Tayebinia, Heidar
Farahani, Farhad
author_sort Mirzaei, Fatemeh
collection PubMed
description This review reported that coronavirus disease 2019 (COVID-19) infected patients with short time bed rest or quarantine and airway inflammation are at more risk of developing hyperglycemia and insulin resistance. This condition can induce oxidative stress, decrease immune system function, impair endothelial function, induce apoptosis, and reduce antioxidant in the lungs. We provide a possible mechanism in severe COVID-19 patients and recommend treatment strategy to reduce mortality rate and prevent adverse outcomes after intensive care unit (ICU).
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spelling pubmed-78342682021-01-26 Importance of hyperglycemia in COVID-19 intensive-care patients: Mechanism and treatment strategy Mirzaei, Fatemeh Khodadadi, Iraj Vafaei, Seyyed Alireza Abbasi-Oshaghi, Ebrahim Tayebinia, Heidar Farahani, Farhad Prim Care Diabetes Review This review reported that coronavirus disease 2019 (COVID-19) infected patients with short time bed rest or quarantine and airway inflammation are at more risk of developing hyperglycemia and insulin resistance. This condition can induce oxidative stress, decrease immune system function, impair endothelial function, induce apoptosis, and reduce antioxidant in the lungs. We provide a possible mechanism in severe COVID-19 patients and recommend treatment strategy to reduce mortality rate and prevent adverse outcomes after intensive care unit (ICU). Primary Care Diabetes Europe. Published by Elsevier Ltd. 2021-06 2021-01-09 /pmc/articles/PMC7834268/ /pubmed/33436320 http://dx.doi.org/10.1016/j.pcd.2021.01.002 Text en © 2021 Primary Care Diabetes Europe. Published by Elsevier Ltd. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Review
Mirzaei, Fatemeh
Khodadadi, Iraj
Vafaei, Seyyed Alireza
Abbasi-Oshaghi, Ebrahim
Tayebinia, Heidar
Farahani, Farhad
Importance of hyperglycemia in COVID-19 intensive-care patients: Mechanism and treatment strategy
title Importance of hyperglycemia in COVID-19 intensive-care patients: Mechanism and treatment strategy
title_full Importance of hyperglycemia in COVID-19 intensive-care patients: Mechanism and treatment strategy
title_fullStr Importance of hyperglycemia in COVID-19 intensive-care patients: Mechanism and treatment strategy
title_full_unstemmed Importance of hyperglycemia in COVID-19 intensive-care patients: Mechanism and treatment strategy
title_short Importance of hyperglycemia in COVID-19 intensive-care patients: Mechanism and treatment strategy
title_sort importance of hyperglycemia in covid-19 intensive-care patients: mechanism and treatment strategy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834268/
https://www.ncbi.nlm.nih.gov/pubmed/33436320
http://dx.doi.org/10.1016/j.pcd.2021.01.002
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