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Differential induction of type I and III interferon genes in the upper respiratory tract of patients with coronavirus disease 2019 (COVID-19)
The natural course of type I and III interferon (IFN) response in the respiratory tract of COVID-19 patients needs to be better defined. We showed that type I/III IFNs, IFN-regulatory factor 7 (IRF7), and IFN stimulated genes (ISGs), are highly expressed in the oropharyngeal cells of SARS-CoV-2 posi...
Autores principales: | Scagnolari, Carolina, Pierangeli, Alessandra, Frasca, Federica, Bitossi, Camilla, Viscido, Agnese, Oliveto, Giuseppe, Scordio, Mirko, Mazzuti, Laura, Di Carlo, Daniele, Gentile, Massimo, Solimini, Angelo, Ceccarelli, Giancarlo, Pugliese, Francesco, Mastroianni, Claudio Maria, d’Ettorre, Gabriella, Turriziani, Ombretta, Antonelli, Guido |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834390/ https://www.ncbi.nlm.nih.gov/pubmed/33418027 http://dx.doi.org/10.1016/j.virusres.2020.198283 |
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