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Mortality and renal outcomes of patients with severe COVID-19 treated in a provisional intensive care unit
COVID-19 has created an enormous health crisis and this spring New York City had a severe outbreak that pushed health and critical care resources to the limit. A lack of adequate space for mechanically ventilated patients induced our hospital to convert operating rooms into critical care areas (OR-I...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834533/ https://www.ncbi.nlm.nih.gov/pubmed/33385774 http://dx.doi.org/10.1016/j.jcrc.2020.12.012 |
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author | Hittesdorf, Erin Panzer, Oliver Wang, David Stevens, Jacob S. Hastie, Jonathan Jordan, Desmond A. Yoh, Nina Eiseman, Katherine A. Elisman, Katerina Wagener, Gebhard |
author_facet | Hittesdorf, Erin Panzer, Oliver Wang, David Stevens, Jacob S. Hastie, Jonathan Jordan, Desmond A. Yoh, Nina Eiseman, Katherine A. Elisman, Katerina Wagener, Gebhard |
author_sort | Hittesdorf, Erin |
collection | PubMed |
description | COVID-19 has created an enormous health crisis and this spring New York City had a severe outbreak that pushed health and critical care resources to the limit. A lack of adequate space for mechanically ventilated patients induced our hospital to convert operating rooms into critical care areas (OR-ICU). A large number of COVID-19 will develop acute kidney injury that requires renal replacement therapy (RRT). We included 116 patients with COVID-19 who required mechanical ventilation and were cared for in our OR-ICU. At 90 days and at discharge 35 patients died (30.2%). RRT was required by 45 of the 116 patients (38.8%) and 18 of these 45 patients (40%) compared to 17 with no RRT (23.9%, ns) died during hospitalization and after 90 days. Only two of the 27 patients who required RRT and survived required RRT at discharge and 90 days. When defining renal recovery as a discharge serum creatinine within 150% of baseline, 68 of 78 survivors showed renal recovery (87.2%). Survival was similar to previous reports of patients with severe COVID-19 for patients cared for in provisional ICUs compared to standard ICUs. Most patients with severe COVID-19 and AKI are likely to recover full renal function. |
format | Online Article Text |
id | pubmed-7834533 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Published by Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78345332021-01-26 Mortality and renal outcomes of patients with severe COVID-19 treated in a provisional intensive care unit Hittesdorf, Erin Panzer, Oliver Wang, David Stevens, Jacob S. Hastie, Jonathan Jordan, Desmond A. Yoh, Nina Eiseman, Katherine A. Elisman, Katerina Wagener, Gebhard J Crit Care Article COVID-19 has created an enormous health crisis and this spring New York City had a severe outbreak that pushed health and critical care resources to the limit. A lack of adequate space for mechanically ventilated patients induced our hospital to convert operating rooms into critical care areas (OR-ICU). A large number of COVID-19 will develop acute kidney injury that requires renal replacement therapy (RRT). We included 116 patients with COVID-19 who required mechanical ventilation and were cared for in our OR-ICU. At 90 days and at discharge 35 patients died (30.2%). RRT was required by 45 of the 116 patients (38.8%) and 18 of these 45 patients (40%) compared to 17 with no RRT (23.9%, ns) died during hospitalization and after 90 days. Only two of the 27 patients who required RRT and survived required RRT at discharge and 90 days. When defining renal recovery as a discharge serum creatinine within 150% of baseline, 68 of 78 survivors showed renal recovery (87.2%). Survival was similar to previous reports of patients with severe COVID-19 for patients cared for in provisional ICUs compared to standard ICUs. Most patients with severe COVID-19 and AKI are likely to recover full renal function. Published by Elsevier Inc. 2021-04 2020-12-19 /pmc/articles/PMC7834533/ /pubmed/33385774 http://dx.doi.org/10.1016/j.jcrc.2020.12.012 Text en © 2020 Published by Elsevier Inc. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Hittesdorf, Erin Panzer, Oliver Wang, David Stevens, Jacob S. Hastie, Jonathan Jordan, Desmond A. Yoh, Nina Eiseman, Katherine A. Elisman, Katerina Wagener, Gebhard Mortality and renal outcomes of patients with severe COVID-19 treated in a provisional intensive care unit |
title | Mortality and renal outcomes of patients with severe COVID-19 treated in a provisional intensive care unit |
title_full | Mortality and renal outcomes of patients with severe COVID-19 treated in a provisional intensive care unit |
title_fullStr | Mortality and renal outcomes of patients with severe COVID-19 treated in a provisional intensive care unit |
title_full_unstemmed | Mortality and renal outcomes of patients with severe COVID-19 treated in a provisional intensive care unit |
title_short | Mortality and renal outcomes of patients with severe COVID-19 treated in a provisional intensive care unit |
title_sort | mortality and renal outcomes of patients with severe covid-19 treated in a provisional intensive care unit |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834533/ https://www.ncbi.nlm.nih.gov/pubmed/33385774 http://dx.doi.org/10.1016/j.jcrc.2020.12.012 |
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