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How would you like your COVID-19? From a host with mild course disease, or from a severe one?

The clinical course of COVID-19 presents a broad spectrum, being asymptomatic in some individuals while following a severe course and resulting in mortality in others. It is known that such factors as age and chronic diseases can result in a different clinical courses in individuals, however, variab...

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Autores principales: Yamanoglu, Adnan, Akyol, Pinar Yeşim, Acar, Hüseyin, Celebi Yamanoglu, Nalan Gokce, Topal, Fatih Esad, Kayalı, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834627/
https://www.ncbi.nlm.nih.gov/pubmed/32536478
http://dx.doi.org/10.1016/j.ajem.2020.05.091
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author Yamanoglu, Adnan
Akyol, Pinar Yeşim
Acar, Hüseyin
Celebi Yamanoglu, Nalan Gokce
Topal, Fatih Esad
Kayalı, Ahmet
author_facet Yamanoglu, Adnan
Akyol, Pinar Yeşim
Acar, Hüseyin
Celebi Yamanoglu, Nalan Gokce
Topal, Fatih Esad
Kayalı, Ahmet
author_sort Yamanoglu, Adnan
collection PubMed
description The clinical course of COVID-19 presents a broad spectrum, being asymptomatic in some individuals while following a severe course and resulting in mortality in others. It is known that such factors as age and chronic diseases can result in a different clinical courses in individuals, however, variable clinical courses among the similar individuals in terms of age and chronic diseases are also seen. Other possible factors affecting the course of the disease that are mostly speculative or under investigation are genetic factors and the origin of transmission or possible subtype of novel coronavirus. Whether the source of transmission is important in the clinical course of the disease is unknown. A case series composed of seven individuals in a similar age group, with different lines of descent and different genetic structures, but who were infected from the same source is presented here. The similar and different clinical, laboratory and radiological findings of the cases residing in the same nursing home, who presented to the hospital altogether, were evaluated. The aim of the study was to analyze whether the source of transmission is influential in the clinical course of the disease.
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spelling pubmed-78346272021-01-26 How would you like your COVID-19? From a host with mild course disease, or from a severe one? Yamanoglu, Adnan Akyol, Pinar Yeşim Acar, Hüseyin Celebi Yamanoglu, Nalan Gokce Topal, Fatih Esad Kayalı, Ahmet Am J Emerg Med Case Report The clinical course of COVID-19 presents a broad spectrum, being asymptomatic in some individuals while following a severe course and resulting in mortality in others. It is known that such factors as age and chronic diseases can result in a different clinical courses in individuals, however, variable clinical courses among the similar individuals in terms of age and chronic diseases are also seen. Other possible factors affecting the course of the disease that are mostly speculative or under investigation are genetic factors and the origin of transmission or possible subtype of novel coronavirus. Whether the source of transmission is important in the clinical course of the disease is unknown. A case series composed of seven individuals in a similar age group, with different lines of descent and different genetic structures, but who were infected from the same source is presented here. The similar and different clinical, laboratory and radiological findings of the cases residing in the same nursing home, who presented to the hospital altogether, were evaluated. The aim of the study was to analyze whether the source of transmission is influential in the clinical course of the disease. Elsevier Inc. 2020-11 2020-06-01 /pmc/articles/PMC7834627/ /pubmed/32536478 http://dx.doi.org/10.1016/j.ajem.2020.05.091 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Case Report
Yamanoglu, Adnan
Akyol, Pinar Yeşim
Acar, Hüseyin
Celebi Yamanoglu, Nalan Gokce
Topal, Fatih Esad
Kayalı, Ahmet
How would you like your COVID-19? From a host with mild course disease, or from a severe one?
title How would you like your COVID-19? From a host with mild course disease, or from a severe one?
title_full How would you like your COVID-19? From a host with mild course disease, or from a severe one?
title_fullStr How would you like your COVID-19? From a host with mild course disease, or from a severe one?
title_full_unstemmed How would you like your COVID-19? From a host with mild course disease, or from a severe one?
title_short How would you like your COVID-19? From a host with mild course disease, or from a severe one?
title_sort how would you like your covid-19? from a host with mild course disease, or from a severe one?
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834627/
https://www.ncbi.nlm.nih.gov/pubmed/32536478
http://dx.doi.org/10.1016/j.ajem.2020.05.091
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