Cargando…
How would you like your COVID-19? From a host with mild course disease, or from a severe one?
The clinical course of COVID-19 presents a broad spectrum, being asymptomatic in some individuals while following a severe course and resulting in mortality in others. It is known that such factors as age and chronic diseases can result in a different clinical courses in individuals, however, variab...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834627/ https://www.ncbi.nlm.nih.gov/pubmed/32536478 http://dx.doi.org/10.1016/j.ajem.2020.05.091 |
_version_ | 1783642325824569344 |
---|---|
author | Yamanoglu, Adnan Akyol, Pinar Yeşim Acar, Hüseyin Celebi Yamanoglu, Nalan Gokce Topal, Fatih Esad Kayalı, Ahmet |
author_facet | Yamanoglu, Adnan Akyol, Pinar Yeşim Acar, Hüseyin Celebi Yamanoglu, Nalan Gokce Topal, Fatih Esad Kayalı, Ahmet |
author_sort | Yamanoglu, Adnan |
collection | PubMed |
description | The clinical course of COVID-19 presents a broad spectrum, being asymptomatic in some individuals while following a severe course and resulting in mortality in others. It is known that such factors as age and chronic diseases can result in a different clinical courses in individuals, however, variable clinical courses among the similar individuals in terms of age and chronic diseases are also seen. Other possible factors affecting the course of the disease that are mostly speculative or under investigation are genetic factors and the origin of transmission or possible subtype of novel coronavirus. Whether the source of transmission is important in the clinical course of the disease is unknown. A case series composed of seven individuals in a similar age group, with different lines of descent and different genetic structures, but who were infected from the same source is presented here. The similar and different clinical, laboratory and radiological findings of the cases residing in the same nursing home, who presented to the hospital altogether, were evaluated. The aim of the study was to analyze whether the source of transmission is influential in the clinical course of the disease. |
format | Online Article Text |
id | pubmed-7834627 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78346272021-01-26 How would you like your COVID-19? From a host with mild course disease, or from a severe one? Yamanoglu, Adnan Akyol, Pinar Yeşim Acar, Hüseyin Celebi Yamanoglu, Nalan Gokce Topal, Fatih Esad Kayalı, Ahmet Am J Emerg Med Case Report The clinical course of COVID-19 presents a broad spectrum, being asymptomatic in some individuals while following a severe course and resulting in mortality in others. It is known that such factors as age and chronic diseases can result in a different clinical courses in individuals, however, variable clinical courses among the similar individuals in terms of age and chronic diseases are also seen. Other possible factors affecting the course of the disease that are mostly speculative or under investigation are genetic factors and the origin of transmission or possible subtype of novel coronavirus. Whether the source of transmission is important in the clinical course of the disease is unknown. A case series composed of seven individuals in a similar age group, with different lines of descent and different genetic structures, but who were infected from the same source is presented here. The similar and different clinical, laboratory and radiological findings of the cases residing in the same nursing home, who presented to the hospital altogether, were evaluated. The aim of the study was to analyze whether the source of transmission is influential in the clinical course of the disease. Elsevier Inc. 2020-11 2020-06-01 /pmc/articles/PMC7834627/ /pubmed/32536478 http://dx.doi.org/10.1016/j.ajem.2020.05.091 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Case Report Yamanoglu, Adnan Akyol, Pinar Yeşim Acar, Hüseyin Celebi Yamanoglu, Nalan Gokce Topal, Fatih Esad Kayalı, Ahmet How would you like your COVID-19? From a host with mild course disease, or from a severe one? |
title | How would you like your COVID-19? From a host with mild course disease, or from a severe one? |
title_full | How would you like your COVID-19? From a host with mild course disease, or from a severe one? |
title_fullStr | How would you like your COVID-19? From a host with mild course disease, or from a severe one? |
title_full_unstemmed | How would you like your COVID-19? From a host with mild course disease, or from a severe one? |
title_short | How would you like your COVID-19? From a host with mild course disease, or from a severe one? |
title_sort | how would you like your covid-19? from a host with mild course disease, or from a severe one? |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834627/ https://www.ncbi.nlm.nih.gov/pubmed/32536478 http://dx.doi.org/10.1016/j.ajem.2020.05.091 |
work_keys_str_mv | AT yamanogluadnan howwouldyoulikeyourcovid19fromahostwithmildcoursediseaseorfromasevereone AT akyolpinaryesim howwouldyoulikeyourcovid19fromahostwithmildcoursediseaseorfromasevereone AT acarhuseyin howwouldyoulikeyourcovid19fromahostwithmildcoursediseaseorfromasevereone AT celebiyamanoglunalangokce howwouldyoulikeyourcovid19fromahostwithmildcoursediseaseorfromasevereone AT topalfatihesad howwouldyoulikeyourcovid19fromahostwithmildcoursediseaseorfromasevereone AT kayalıahmet howwouldyoulikeyourcovid19fromahostwithmildcoursediseaseorfromasevereone |