Evaluation of SARS-CoV-2 3C-like protease inhibitors using self-assembled monolayer desorption ionization mass spectrometry

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-19 pandemic that began in 2019. The coronavirus 3-chymotrypsin-like cysteine protease (3CLpro) controls replication and is therefore considered a major target for antiviral discovery. This study describes the eval...

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Detalles Bibliográficos
Autores principales: Gurard-Levin, Zachary A., Liu, Cheng, Jekle, Andreas, Jaisinghani, Ruchika, Ren, Suping, Vandyck, Koen, Jochmans, Dirk, Leyssen, Pieter, Neyts, Johan, Blatt, Lawrence M., Beigelman, Leonid, Symons, Julian A., Raboisson, Pierre, Scholle, Michael D., Deval, Jerome
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834858/
https://www.ncbi.nlm.nih.gov/pubmed/32896566
http://dx.doi.org/10.1016/j.antiviral.2020.104924

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