The 1316T>C missenses mutation in MTHFR contributes to MTHFR deficiency by targeting MTHFR to proteasome degradation

5,10-methylenetetrahydrofolate reductase (MTHFR) deficiency is a rare hereditary disease characterized by defects in folate and homocysteine metabolism. Individuals with inherited MTHFR gene mutations have a higher tendency to develop neurodegeneration disease as Alzheimer’ disease and atheroscleros...

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Detalles Bibliográficos
Autores principales: Liu, Xi, Li, Yu, Wang, Menghan, Wang, Xiaojun, Zhang, Limin, Peng, Tao, Liang, Wenping, Wang, Zhe, Lu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7834980/
https://www.ncbi.nlm.nih.gov/pubmed/33290257
http://dx.doi.org/10.18632/aging.202256

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