High-fat diet induced discrepant peripheral and central nervous systems insulin resistance in APPswe/PS1dE9 and wild-type C57BL/6J mice

This study was designed to examine whether AD pathological phenotype in APPswe/PS1dE9 (APP/PS1) mice exposed to continuous high-fat diet predispose these murine models to metabolic dysfunction and neuropathological impairments. One-month old male APP/PS1 and C57BL/6J mice were provided with 60% high...

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Detalles Bibliográficos
Autores principales: Guo, Yujie, Ma, Xiaojun, Li, Pengfei, Dong, Shengqi, Huang, Xiaochen, Ren, Xiuwen, Yuan, Linhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835010/
https://www.ncbi.nlm.nih.gov/pubmed/33291072
http://dx.doi.org/10.18632/aging.202262

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