In vivo imaging of CNS microglial activation/macrophage infiltration with combined [(18)F]DPA-714-PET and SPIO-MRI in a mouse model of relapsing remitting experimental autoimmune encephalomyelitis

PURPOSE: To evaluate the feasibility and sensitivity of multimodality PET/CT and MRI imaging for non-invasive characterization of brain microglial/macrophage activation occurring during the acute phase in a mouse model of relapsing remitting multiple sclerosis (RR-MS) using [(18)F]DPA-714, a selecti...

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Detalles Bibliográficos
Autores principales: Coda, A. R., Anzilotti, S., Boscia, F., Greco, A., Panico, M., Gargiulo, S., Gramanzini, M., Zannetti, A., Albanese, S., Pignataro, G., Annunziato, L., Salvatore, M., Brunetti, A., De Berardinis, P., Quarantelli, Mario, Palma, G., Pappatà, Sabina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835304/
https://www.ncbi.nlm.nih.gov/pubmed/32378022
http://dx.doi.org/10.1007/s00259-020-04842-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835304/
https://www.ncbi.nlm.nih.gov/pubmed/32378022
http://dx.doi.org/10.1007/s00259-020-04842-7

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