Cargando…
Bioinspired Modifications of PEEK Implants for Bone Tissue Engineering
In recent years, polyetheretherketone (PEEK) has been increasingly employed as an implant material in clinical applications. Although PEEK is biocompatible, chemically stable, and radiolucent and has an elastic modulus similar to that of natural bone, it suffers from poor integration with surroundin...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835420/ https://www.ncbi.nlm.nih.gov/pubmed/33511108 http://dx.doi.org/10.3389/fbioe.2020.631616 |
_version_ | 1783642522494435328 |
---|---|
author | Gu, Xinming Sun, Xiaolin Sun, Yue Wang, Jia Liu, Yiping Yu, Kaixuan Wang, Yao Zhou, Yanmin |
author_facet | Gu, Xinming Sun, Xiaolin Sun, Yue Wang, Jia Liu, Yiping Yu, Kaixuan Wang, Yao Zhou, Yanmin |
author_sort | Gu, Xinming |
collection | PubMed |
description | In recent years, polyetheretherketone (PEEK) has been increasingly employed as an implant material in clinical applications. Although PEEK is biocompatible, chemically stable, and radiolucent and has an elastic modulus similar to that of natural bone, it suffers from poor integration with surrounding bone tissue after implantation. To improve the bioactivity of PEEK, numerous strategies for functionalizing the PEEK surface and changing the PEEK structure have been proposed. Inspired by the components, structure, and function of bone tissue, this review discusses strategies to enhance the biocompatibility of PEEK implants and provides direction for fabricating multifunctional implants in the future. |
format | Online Article Text |
id | pubmed-7835420 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78354202021-01-27 Bioinspired Modifications of PEEK Implants for Bone Tissue Engineering Gu, Xinming Sun, Xiaolin Sun, Yue Wang, Jia Liu, Yiping Yu, Kaixuan Wang, Yao Zhou, Yanmin Front Bioeng Biotechnol Bioengineering and Biotechnology In recent years, polyetheretherketone (PEEK) has been increasingly employed as an implant material in clinical applications. Although PEEK is biocompatible, chemically stable, and radiolucent and has an elastic modulus similar to that of natural bone, it suffers from poor integration with surrounding bone tissue after implantation. To improve the bioactivity of PEEK, numerous strategies for functionalizing the PEEK surface and changing the PEEK structure have been proposed. Inspired by the components, structure, and function of bone tissue, this review discusses strategies to enhance the biocompatibility of PEEK implants and provides direction for fabricating multifunctional implants in the future. Frontiers Media S.A. 2021-01-12 /pmc/articles/PMC7835420/ /pubmed/33511108 http://dx.doi.org/10.3389/fbioe.2020.631616 Text en Copyright © 2021 Gu, Sun, Sun, Wang, Liu, Yu, Wang and Zhou. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Bioengineering and Biotechnology Gu, Xinming Sun, Xiaolin Sun, Yue Wang, Jia Liu, Yiping Yu, Kaixuan Wang, Yao Zhou, Yanmin Bioinspired Modifications of PEEK Implants for Bone Tissue Engineering |
title | Bioinspired Modifications of PEEK Implants for Bone Tissue Engineering |
title_full | Bioinspired Modifications of PEEK Implants for Bone Tissue Engineering |
title_fullStr | Bioinspired Modifications of PEEK Implants for Bone Tissue Engineering |
title_full_unstemmed | Bioinspired Modifications of PEEK Implants for Bone Tissue Engineering |
title_short | Bioinspired Modifications of PEEK Implants for Bone Tissue Engineering |
title_sort | bioinspired modifications of peek implants for bone tissue engineering |
topic | Bioengineering and Biotechnology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835420/ https://www.ncbi.nlm.nih.gov/pubmed/33511108 http://dx.doi.org/10.3389/fbioe.2020.631616 |
work_keys_str_mv | AT guxinming bioinspiredmodificationsofpeekimplantsforbonetissueengineering AT sunxiaolin bioinspiredmodificationsofpeekimplantsforbonetissueengineering AT sunyue bioinspiredmodificationsofpeekimplantsforbonetissueengineering AT wangjia bioinspiredmodificationsofpeekimplantsforbonetissueengineering AT liuyiping bioinspiredmodificationsofpeekimplantsforbonetissueengineering AT yukaixuan bioinspiredmodificationsofpeekimplantsforbonetissueengineering AT wangyao bioinspiredmodificationsofpeekimplantsforbonetissueengineering AT zhouyanmin bioinspiredmodificationsofpeekimplantsforbonetissueengineering |