Multiple Cerebral Infarction Associated with Cerebral Vasculitis in a Patient with Ulcerative Colitis

A 40-year-old man was admitted to the hospital due to both a worsening of symptoms associated with ulcerative colitis (UC), which had been diagnosed 3 years previously, and limb paralysis. Colonoscopy revealed severe pancolitis-type UC. He was diagnosed with cerebral vasculitis with multiple white m...

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Detalles Bibliográficos
Autores principales: Yasuda, Takeshi, Takagi, Tomohisa, Hasegawa, Daisuke, Hirose, Ryohei, Inoue, Ken, Dohi, Osamu, Yoshida, Naohisa, Kamada, Kazuhiro, Uchiyama, Kazuhiko, Ishikawa, Takeshi, Konishi, Hideyuki, Naito, Yuji, Itoh, Yoshito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835462/
https://www.ncbi.nlm.nih.gov/pubmed/32830176
http://dx.doi.org/10.2169/internalmedicine.4951-20
Descripción
Sumario:A 40-year-old man was admitted to the hospital due to both a worsening of symptoms associated with ulcerative colitis (UC), which had been diagnosed 3 years previously, and limb paralysis. Colonoscopy revealed severe pancolitis-type UC. He was diagnosed with cerebral vasculitis with multiple white matter infarctions associated with the disease activity of UC by contrast-enhanced head magnetic resonance imaging. Mesalazine at 4,000 mg/day and prednisolone at 60 mg/day were started, and the prednisolone dosage was thereafter gradually reduced and switched to golimumab. He achieved a long-term remission from UC, and thereafter his neurological abnormalities improved significantly. He had no recurrence of cerebral infarction.

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