Bradycardia Shock Caused by the Combined Use of Carteolol Eye Drops and Verapamil in an Elderly Patient with Atrial Fibrillation and Chronic Kidney Disease

Ophthalmic carteolol is often used to treat glaucoma. Elderly patients with atrial fibrillation (AF) and chronic kidney disease (CKD) are common among the super-elderly in Japan. Because these patients are exposed to polypharmacy, they are at a high-risk of adverse drug interactions. We herein repor...

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Autores principales: Arai, Riku, Fukamachi, Daisuke, Monden, Masaki, Akutsu, Naotaka, Murata, Nobuhiro, Okumura, Yasuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835476/
https://www.ncbi.nlm.nih.gov/pubmed/32830185
http://dx.doi.org/10.2169/internalmedicine.5598-20
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author Arai, Riku
Fukamachi, Daisuke
Monden, Masaki
Akutsu, Naotaka
Murata, Nobuhiro
Okumura, Yasuo
author_facet Arai, Riku
Fukamachi, Daisuke
Monden, Masaki
Akutsu, Naotaka
Murata, Nobuhiro
Okumura, Yasuo
author_sort Arai, Riku
collection PubMed
description Ophthalmic carteolol is often used to treat glaucoma. Elderly patients with atrial fibrillation (AF) and chronic kidney disease (CKD) are common among the super-elderly in Japan. Because these patients are exposed to polypharmacy, they are at a high-risk of adverse drug interactions. We herein report an elderly patient with CKD who suffered bradycardia shock after the combined use of carteolol eye drops and verapamil for glaucoma and paroxysmal AF. This case highlights the fact that eye drops have a similar systemic effect to oral drugs, and especially in elderly patients with polypharmacy, drug interactions can unwittingly lead to serious events.
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spelling pubmed-78354762021-02-04 Bradycardia Shock Caused by the Combined Use of Carteolol Eye Drops and Verapamil in an Elderly Patient with Atrial Fibrillation and Chronic Kidney Disease Arai, Riku Fukamachi, Daisuke Monden, Masaki Akutsu, Naotaka Murata, Nobuhiro Okumura, Yasuo Intern Med Case Report Ophthalmic carteolol is often used to treat glaucoma. Elderly patients with atrial fibrillation (AF) and chronic kidney disease (CKD) are common among the super-elderly in Japan. Because these patients are exposed to polypharmacy, they are at a high-risk of adverse drug interactions. We herein report an elderly patient with CKD who suffered bradycardia shock after the combined use of carteolol eye drops and verapamil for glaucoma and paroxysmal AF. This case highlights the fact that eye drops have a similar systemic effect to oral drugs, and especially in elderly patients with polypharmacy, drug interactions can unwittingly lead to serious events. The Japanese Society of Internal Medicine 2020-08-22 2021-01-01 /pmc/articles/PMC7835476/ /pubmed/32830185 http://dx.doi.org/10.2169/internalmedicine.5598-20 Text en Copyright © 2021 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/ The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Arai, Riku
Fukamachi, Daisuke
Monden, Masaki
Akutsu, Naotaka
Murata, Nobuhiro
Okumura, Yasuo
Bradycardia Shock Caused by the Combined Use of Carteolol Eye Drops and Verapamil in an Elderly Patient with Atrial Fibrillation and Chronic Kidney Disease
title Bradycardia Shock Caused by the Combined Use of Carteolol Eye Drops and Verapamil in an Elderly Patient with Atrial Fibrillation and Chronic Kidney Disease
title_full Bradycardia Shock Caused by the Combined Use of Carteolol Eye Drops and Verapamil in an Elderly Patient with Atrial Fibrillation and Chronic Kidney Disease
title_fullStr Bradycardia Shock Caused by the Combined Use of Carteolol Eye Drops and Verapamil in an Elderly Patient with Atrial Fibrillation and Chronic Kidney Disease
title_full_unstemmed Bradycardia Shock Caused by the Combined Use of Carteolol Eye Drops and Verapamil in an Elderly Patient with Atrial Fibrillation and Chronic Kidney Disease
title_short Bradycardia Shock Caused by the Combined Use of Carteolol Eye Drops and Verapamil in an Elderly Patient with Atrial Fibrillation and Chronic Kidney Disease
title_sort bradycardia shock caused by the combined use of carteolol eye drops and verapamil in an elderly patient with atrial fibrillation and chronic kidney disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835476/
https://www.ncbi.nlm.nih.gov/pubmed/32830185
http://dx.doi.org/10.2169/internalmedicine.5598-20
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