Niche Modulation of IGF-1R Signaling: Its Role in Stem Cell Pluripotency, Cancer Reprogramming, and Therapeutic Applications

Stem cells work with their niches harmoniously during development. This concept has been extended to cancer pathology for cancer stem cells (CSCs) or cancer reprogramming. IGF-1R, a classical survival signaling, has been shown to regulate stem cell pluripotency, CSCs, or cancer reprogramming. The me...

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Detalles Bibliográficos
Autores principales: Chen, Pei-Chin, Kuo, Yung-Che, Chuong, Cheng-Ming, Huang, Yen-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835526/
https://www.ncbi.nlm.nih.gov/pubmed/33511137
http://dx.doi.org/10.3389/fcell.2020.625943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835526/
https://www.ncbi.nlm.nih.gov/pubmed/33511137
http://dx.doi.org/10.3389/fcell.2020.625943

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