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Stem Cell Factor in Combination With Granulocyte Colony-Stimulating Factor Protects the Brain From Capillary Thrombosis-Induced Ischemic Neuron Loss in a Mouse Model of CADASIL
Cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy (CADASIL) is a Notch3 mutation-induced cerebral small vessel disease, leading to recurrent ischemic stroke and vascular dementia. There is currently no treatment that can stop or delay CADASIL progression. We h...
Autores principales: | Ping, Suning, Qiu, Xuecheng, Gonzalez-Toledo, Maria E., Liu, Xiaoyun, Zhao, Li-Ru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835527/ https://www.ncbi.nlm.nih.gov/pubmed/33511138 http://dx.doi.org/10.3389/fcell.2020.627733 |
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