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Prkaa1 Metabolically Regulates Monocyte/Macrophage Recruitment and Viability in Diet-Induced Murine Metabolic Disorders
Myeloid cells, including monocytes/macrophages, primarily rely on glucose and lipid metabolism to provide the energy and metabolites needed for their functions and survival. AMP-activated protein kinase (AMPK, its gene is PRKA for human, Prka for rodent) is a key metabolic sensor that regulates many...
Autores principales: | Yang, Qiuhua, Ma, Qian, Xu, Jiean, Liu, Zhiping, Zou, Jianqiu, Shen, Jian, Zhou, Yaqi, Da, Qingen, Mao, Xiaoxiao, Lu, Sarah, Fulton, David J., Weintraub, Neal L., Bagi, Zsolt, Hong, Mei, Huo, Yuqing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835533/ https://www.ncbi.nlm.nih.gov/pubmed/33511118 http://dx.doi.org/10.3389/fcell.2020.611354 |
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