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Myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2
A 6‐year‐old African boy with multi‐viral infection including parvovirus B19 and severe acute respiratory syndrome coronavirus 2 was admitted for persistent fever associated with respiratory distress and myocarditis complicated by cardiogenic shock needing ventilatory and inotropic support. Coronary...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835580/ https://www.ncbi.nlm.nih.gov/pubmed/33332751 http://dx.doi.org/10.1002/ehf2.13048 |
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author | Ciuca, Cristina Fabi, Marianna Di Luca, Daniela Niro, Fabio Ghizzi, Chiara Donti, Andrea Balducci, Anna Rocca, Alessandro Zarbo, Chiara Gargiulo, Gaetano Domenico Lanari, Marcello |
author_facet | Ciuca, Cristina Fabi, Marianna Di Luca, Daniela Niro, Fabio Ghizzi, Chiara Donti, Andrea Balducci, Anna Rocca, Alessandro Zarbo, Chiara Gargiulo, Gaetano Domenico Lanari, Marcello |
author_sort | Ciuca, Cristina |
collection | PubMed |
description | A 6‐year‐old African boy with multi‐viral infection including parvovirus B19 and severe acute respiratory syndrome coronavirus 2 was admitted for persistent fever associated with respiratory distress and myocarditis complicated by cardiogenic shock needing ventilatory and inotropic support. Coronary aneurysms were also documented in the acute phase. Blood tests were suggestive of macrophage activation syndrome. He was treated with intravenous immunoglobulins, aspirin, diuretics, dexamethasone, hydroxychloroquine, and prophylactic low molecular weight heparin. Normalization of cardiac performance and coronary diameters was noticed within the first days. Cardiac magnetic resonance imaging, performed 20 days after the hospitalization, evidenced mild myocardial interstitial oedema with no focal necrosis, suggesting a mechanism of cardiac stunning related to cytokines storm rather than direct viral injury of cardiomyocytes. |
format | Online Article Text |
id | pubmed-7835580 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-78355802021-02-01 Myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2 Ciuca, Cristina Fabi, Marianna Di Luca, Daniela Niro, Fabio Ghizzi, Chiara Donti, Andrea Balducci, Anna Rocca, Alessandro Zarbo, Chiara Gargiulo, Gaetano Domenico Lanari, Marcello ESC Heart Fail Case Reports A 6‐year‐old African boy with multi‐viral infection including parvovirus B19 and severe acute respiratory syndrome coronavirus 2 was admitted for persistent fever associated with respiratory distress and myocarditis complicated by cardiogenic shock needing ventilatory and inotropic support. Coronary aneurysms were also documented in the acute phase. Blood tests were suggestive of macrophage activation syndrome. He was treated with intravenous immunoglobulins, aspirin, diuretics, dexamethasone, hydroxychloroquine, and prophylactic low molecular weight heparin. Normalization of cardiac performance and coronary diameters was noticed within the first days. Cardiac magnetic resonance imaging, performed 20 days after the hospitalization, evidenced mild myocardial interstitial oedema with no focal necrosis, suggesting a mechanism of cardiac stunning related to cytokines storm rather than direct viral injury of cardiomyocytes. John Wiley and Sons Inc. 2020-12-17 /pmc/articles/PMC7835580/ /pubmed/33332751 http://dx.doi.org/10.1002/ehf2.13048 Text en © 2020 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Case Reports Ciuca, Cristina Fabi, Marianna Di Luca, Daniela Niro, Fabio Ghizzi, Chiara Donti, Andrea Balducci, Anna Rocca, Alessandro Zarbo, Chiara Gargiulo, Gaetano Domenico Lanari, Marcello Myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2 |
title | Myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2 |
title_full | Myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2 |
title_fullStr | Myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2 |
title_full_unstemmed | Myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2 |
title_short | Myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2 |
title_sort | myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2 |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835580/ https://www.ncbi.nlm.nih.gov/pubmed/33332751 http://dx.doi.org/10.1002/ehf2.13048 |
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