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Myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2

A 6‐year‐old African boy with multi‐viral infection including parvovirus B19 and severe acute respiratory syndrome coronavirus 2 was admitted for persistent fever associated with respiratory distress and myocarditis complicated by cardiogenic shock needing ventilatory and inotropic support. Coronary...

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Autores principales: Ciuca, Cristina, Fabi, Marianna, Di Luca, Daniela, Niro, Fabio, Ghizzi, Chiara, Donti, Andrea, Balducci, Anna, Rocca, Alessandro, Zarbo, Chiara, Gargiulo, Gaetano Domenico, Lanari, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835580/
https://www.ncbi.nlm.nih.gov/pubmed/33332751
http://dx.doi.org/10.1002/ehf2.13048
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author Ciuca, Cristina
Fabi, Marianna
Di Luca, Daniela
Niro, Fabio
Ghizzi, Chiara
Donti, Andrea
Balducci, Anna
Rocca, Alessandro
Zarbo, Chiara
Gargiulo, Gaetano Domenico
Lanari, Marcello
author_facet Ciuca, Cristina
Fabi, Marianna
Di Luca, Daniela
Niro, Fabio
Ghizzi, Chiara
Donti, Andrea
Balducci, Anna
Rocca, Alessandro
Zarbo, Chiara
Gargiulo, Gaetano Domenico
Lanari, Marcello
author_sort Ciuca, Cristina
collection PubMed
description A 6‐year‐old African boy with multi‐viral infection including parvovirus B19 and severe acute respiratory syndrome coronavirus 2 was admitted for persistent fever associated with respiratory distress and myocarditis complicated by cardiogenic shock needing ventilatory and inotropic support. Coronary aneurysms were also documented in the acute phase. Blood tests were suggestive of macrophage activation syndrome. He was treated with intravenous immunoglobulins, aspirin, diuretics, dexamethasone, hydroxychloroquine, and prophylactic low molecular weight heparin. Normalization of cardiac performance and coronary diameters was noticed within the first days. Cardiac magnetic resonance imaging, performed 20 days after the hospitalization, evidenced mild myocardial interstitial oedema with no focal necrosis, suggesting a mechanism of cardiac stunning related to cytokines storm rather than direct viral injury of cardiomyocytes.
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spelling pubmed-78355802021-02-01 Myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2 Ciuca, Cristina Fabi, Marianna Di Luca, Daniela Niro, Fabio Ghizzi, Chiara Donti, Andrea Balducci, Anna Rocca, Alessandro Zarbo, Chiara Gargiulo, Gaetano Domenico Lanari, Marcello ESC Heart Fail Case Reports A 6‐year‐old African boy with multi‐viral infection including parvovirus B19 and severe acute respiratory syndrome coronavirus 2 was admitted for persistent fever associated with respiratory distress and myocarditis complicated by cardiogenic shock needing ventilatory and inotropic support. Coronary aneurysms were also documented in the acute phase. Blood tests were suggestive of macrophage activation syndrome. He was treated with intravenous immunoglobulins, aspirin, diuretics, dexamethasone, hydroxychloroquine, and prophylactic low molecular weight heparin. Normalization of cardiac performance and coronary diameters was noticed within the first days. Cardiac magnetic resonance imaging, performed 20 days after the hospitalization, evidenced mild myocardial interstitial oedema with no focal necrosis, suggesting a mechanism of cardiac stunning related to cytokines storm rather than direct viral injury of cardiomyocytes. John Wiley and Sons Inc. 2020-12-17 /pmc/articles/PMC7835580/ /pubmed/33332751 http://dx.doi.org/10.1002/ehf2.13048 Text en © 2020 The Authors. ESC Heart Failure published by John Wiley & Sons Ltd on behalf of the European Society of Cardiology This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Ciuca, Cristina
Fabi, Marianna
Di Luca, Daniela
Niro, Fabio
Ghizzi, Chiara
Donti, Andrea
Balducci, Anna
Rocca, Alessandro
Zarbo, Chiara
Gargiulo, Gaetano Domenico
Lanari, Marcello
Myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2
title Myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2
title_full Myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2
title_fullStr Myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2
title_full_unstemmed Myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2
title_short Myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2
title_sort myocarditis and coronary aneurysms in a child with acute respiratory syndrome coronavirus 2
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835580/
https://www.ncbi.nlm.nih.gov/pubmed/33332751
http://dx.doi.org/10.1002/ehf2.13048
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