The Crucial Role of Demannosylating Asparagine-Linked Glycans in ERADicating Misfolded Glycoproteins in the Endoplasmic Reticulum

Most membrane and secreted proteins are glycosylated on certain asparagine (N) residues in the endoplasmic reticulum (ER), which is crucial for their correct folding and function. Protein folding is a fundamentally inefficient and error-prone process that can be easily interfered by genetic mutation...

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Detalles Bibliográficos
Autores principales: Zhang, Jianjun, Wu, Jiarui, Liu, Linchuan, Li, Jianming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Plant Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835635/
https://www.ncbi.nlm.nih.gov/pubmed/33510762
http://dx.doi.org/10.3389/fpls.2020.625033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835635/
https://www.ncbi.nlm.nih.gov/pubmed/33510762
http://dx.doi.org/10.3389/fpls.2020.625033

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