Cargando…

Metabolic Profile of Four Selected Cathinones in Microsome Incubations: Identification of Phase I and II Metabolites by Liquid Chromatography High Resolution Mass Spectrometry

Consumption of synthetic cathinones, the second largest class of new psychoactive substances (NPS) reported worldwide, represents a serious public health risk. One of the biggest challenges created by the rapid spread of NPS on the illegal drug market is the discovery of selective biomarkers for the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lopes, Beatriz T., Caldeira, Maria João, Gaspar, Helena, Antunes, Alexandra M. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835677/ https://www.ncbi.nlm.nih.gov/pubmed/33511100 http://dx.doi.org/10.3389/fchem.2020.609251

Ejemplares similares

Metabolic stability and metabolite profiling of emerging synthetic cathinones
por: Lopes, Rita P., et al.
Publicado: (2023)

Liquid Chromatography-High-Resolution Mass Spectrometry-Based In Vitro Toxicometabolomics of the Synthetic Cathinones 4-MPD and 4-MEAP in Pooled Human Liver Microsomes
por: Manier, Sascha K., et al.
Publicado: (2020)

Identification of Erythromycin and Clarithromycin Metabolites Formed in Chicken Liver Microsomes Using Liquid Chromatography–High-Resolution Mass Spectrometry
por: Wang, Bo, et al.
Publicado: (2021)

Structure Assignment of Seized Products Containing Cathinone Derivatives Using High Resolution Analytical Techniques
por: Gonçalves, João L., et al.
Publicado: (2021)

Analysis of AMB-FUBINACA Biotransformation Pathways in Human Liver Microsome and Zebrafish Systems by Liquid Chromatography-High Resolution Mass Spectrometry
por: Xu, Duo-qi, et al.
Publicado: (2019)

Pyrrolidinyl Synthetic Cathinones α-PHP and 4F-α-PVP Metabolite Profiling Using Human Hepatocyte Incubations
por: Carlier, Jeremy, et al.
Publicado: (2020)

Metabolic profiling of four synthetic stimulants, including the novel indanyl-cathinone 5-PPDi, after human hepatocyte incubation
por: Fabregat-Safont, David, et al.
Publicado: (2020)

In vitro metabolism of synthetic cannabinoid AM1220 by human liver microsomes and Cunninghamella elegans using liquid chromatography coupled with high resolution mass spectrometry
por: Watanabe, Shimpei, et al.
Publicado: (2018)

Identification of Auxin Metabolites in Brassicaceae by Ultra-Performance Liquid Chromatography Coupled with High-Resolution Mass Spectrometry
por: Revelou, Panagiota-Kyriaki, et al.
Publicado: (2019)

Identification of the New Metabolite of Nebivolol Using Liquid Chromatography Coupled with High-Resolution Mass Spectrometry and Chemometrics
por: Trawiński, Jakub, et al.
Publicado: (2022)

Study of in-vitro metabolism of selected antibiotic drugs in human liver microsomes by liquid chromatography coupled with tandem mass spectrometry
por: Szultka-Mlynska, Malgorzata, et al.
Publicado: (2016)

Combined Liquid Chromatography–Tandem Mass Spectrometry Analysis of Progesterone Metabolites
por: Sinreih, Maša, et al.
Publicado: (2015)

Simultaneous Determination and Stability Analysis of Ten New Psychoactive Substances including Synthetic Cathinones, Phenethylamines, and Ketamine Substitutes in Urine Using Liquid Chromatography-Tandem Mass Spectrometry
por: Yang, Feng-Shuo, et al.
Publicado: (2023)

Delivery prediction by quantitative analysis of four steroid metabolites with liquid chromatography tandem mass spectrometry in asymptomatic pregnant women
por: Meng, Lanlan, et al.
Publicado: (2022)

A Rough Guide to Metabolite Identification Using High Resolution Liquid Chromatography Mass Spectrometry in Metabolomic Profiling in Metazoans
por: Watson, David G.
Publicado: (2013)

Analysis of benzo[a]pyrene metabolites formed by rat hepatic microsomes using high pressure liquid chromatography: optimization of the method
por: Moserová, Michaela, et al.
Publicado: (2009)

Liquid chromatography tandem mass spectrometry method for the quantification of vandetanib in human plasma and rat liver microsomes matrices: metabolic stability investigation
por: Amer, Sawsan M., et al.
Publicado: (2017)

Metabolite Profiling of the Antisense Oligonucleotide Eluforsen Using Liquid Chromatography-Mass Spectrometry
por: Kim, Jaeah, et al.
Publicado: (2019)

NADomics: Measuring NAD(+) and Related Metabolites Using Liquid Chromatography Mass Spectrometry
por: Braidy, Nady, et al.
Publicado: (2021)

Characterization of Phase I and Glucuronide Phase II Metabolites of 17 Mycotoxins Using Liquid Chromatography—High-Resolution Mass Spectrometry
por: Slobodchikova, Irina, et al.
Publicado: (2019)

Comprehensive Metabolite Identification of Genipin in Rats Using Ultra-High-Performance Liquid Chromatography Coupled with High Resolution Mass Spectrometry
por: Cui, Zhifeng, et al.
Publicado: (2023)

Ultra-High Performance Liquid Chromatography-High Resolution Mass Spectrometry and High-Sensitivity Gas Chromatography-Mass Spectrometry Screening of Classic Drugs and New Psychoactive Substances and Metabolites in Urine of Consumers
por: Marchei, Emilia, et al.
Publicado: (2021)

Identification of New Metabolites of Bacterial Transformation of Indole by Gas Chromatography-Mass Spectrometry and High Performance Liquid Chromatography
por: Arora, Pankaj Kumar, et al.
Publicado: (2014)

Identification of a Radical Formed in the Reaction Mixtures of Ram Seminal Vesicle Microsomes with Arachidonic Acid Using High Performance Liquid Chromatography-Electron Spin Resonance Spectrometry and High Performance Liquid Chromatography-Electron Spin Resonance-Mass Spectrometry
por: Minakata, Katsuyuki, et al.
Publicado: (2010)

Identification of Trenbolone Metabolites Using Hydrogen Isotope Ratio Mass Spectrometry and Liquid Chromatography/High Accuracy/High Resolution Mass Spectrometry for Doping Control Analysis
por: Putz, Marlen, et al.
Publicado: (2020)

The Pharmacological Profile of Second Generation Pyrovalerone Cathinones and Related Cathinone Derivative
por: Kolaczynska, Karolina E., et al.
Publicado: (2021)

Automated Label-free Quantification of Metabolites from Liquid Chromatography–Mass Spectrometry Data
por: Kenar, Erhan, et al.
Publicado: (2014)

Simultaneous Quantification of Multiple Urinary Naphthalene Metabolites by Liquid Chromatography Tandem Mass Spectrometry
por: Ayala, Daniel C., et al.
Publicado: (2015)

Profiling of serum metabolites in advanced colon cancer using liquid chromatography-mass spectrometry
por: Zhang, Yang, et al.
Publicado: (2020)

Identification of cerebrospinal fluid metabolites as biomarkers for neurobrucellosis by liquid chromatography-mass spectrometry approach
por: Yang, Hao, et al.
Publicado: (2022)

Circulating Conjugated and Unconjugated Vitamin D Metabolite Measurements by Liquid Chromatography Mass Spectrometry
por: Jenkinson, Carl, et al.
Publicado: (2021)

Ensuring Fact-Based Metabolite Identification in Liquid Chromatography–Mass Spectrometry-Based Metabolomics
por: Theodoridis, Georgios, et al.
Publicado: (2023)

Phylogenetic Studies and Metabolite Analysis of Sticta Species from Colombia and Chile by Ultra-High Performance Liquid Chromatography-High Resolution-Q-Orbitrap-Mass Spectrometry
por: Albornoz, Laura, et al.
Publicado: (2022)

Synthetic cathinone abuse
por: Capriola, Michael
Publicado: (2013)

A comparison of four liquid chromatography–mass spectrometry platforms for the analysis of zeranols in urine
por: Lazofsky, Abigail, et al.
Publicado: (2023)

Untargeted metabolite profiling on the water-soluble metabolites of edible bird’s nest through liquid chromatography-mass spectrometry
por: Tong, Shi-Ruo, et al.
Publicado: (2020)

Ultra Performance Liquid Chromatography and High Resolution Mass Spectrometry for the Analysis of Plant Lipids
por: Hummel, Jan, et al.
Publicado: (2011)

Characterization of Fumonisin A-Series by High-Resolution Liquid Chromatography-Orbitrap Mass Spectrometry
por: Tamura, Masayoshi, et al.
Publicado: (2014)

Ultra-Trace Analysis of Cyanotoxins by Liquid Chromatography Coupled to High-Resolution Mass Spectrometry
por: Filatova, Daria, et al.
Publicado: (2020)

Adduct annotation in liquid chromatography/high-resolution mass spectrometry to enhance compound identification
por: Stricker, Thomas, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_l46ff9aab089fumhat8hlvpco1