Pathological ATX3 Expression Induces Cell Perturbations in E. coli as Revealed by Biochemical and Biophysical Investigations

Amyloid aggregation of human ataxin-3 (ATX3) is responsible for spinocerebellar ataxia type 3, which belongs to the class of polyglutamine neurodegenerative disorders. It is widely accepted that the formation of toxic oligomeric species is primarily involved in the onset of the disease. For this rea...

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Detalles Bibliográficos
Autores principales: Ami, Diletta, Sciandrone, Barbara, Mereghetti, Paolo, Falvo, Jacopo, Catelani, Tiziano, Visentin, Cristina, Tortora, Paolo, Ventura, Salvador, Natalello, Antonino, Regonesi, Maria Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835732/
https://www.ncbi.nlm.nih.gov/pubmed/33477953
http://dx.doi.org/10.3390/ijms22020943

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835732/
https://www.ncbi.nlm.nih.gov/pubmed/33477953
http://dx.doi.org/10.3390/ijms22020943

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