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Discovery of Functional Alternatively Spliced PKM Transcripts in Human Cancers

SIMPLE SUMMARY: Pyruvate kinase muscle type (PKM) is a key enzyme in glycolysis and is a mediator of the Warburg effect in tumors. The association of PKM with survival of cancer patients is controversial. In this study, we investigated the associations of the alternatively spliced transcripts of PKM...

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Detalles Bibliográficos
Autores principales: Li, Xiangyu, Kim, Woonghee, Arif, Muhammad, Gao, Chunxia, Hober, Andreas, Kotol, David, Strandberg, Linnéa, Forsström, Björn, Sivertsson, Åsa, Oksvold, Per, Turkez, Hasan, Grøtli, Morten, Sato, Yusuke, Kume, Haruki, Ogawa, Seishi, Boren, Jan, Nielsen, Jens, Uhlen, Mathias, Zhang, Cheng, Mardinoglu, Adil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835739/
https://www.ncbi.nlm.nih.gov/pubmed/33478099
http://dx.doi.org/10.3390/cancers13020348