Detection of Mitochondrial Mutations Through Isothermal Nucleic Acid Amplification Coupled With Clustered Regularly Interspaced Short Palindromic Repeat-Associated Endonuclease Cas13a

The clustered regularly interspaced short palindromic repeat (CRISPR)-associated endonuclease Cas13a can specifically bind and cleave RNA. After nucleic acid pre-amplification, bacterial Cas13a has been used to detect genetic mutations. In our study, using a transcription-mediated amplification toge...

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Detalles Bibliográficos
Autores principales: Jiang, Hua, Duan, Kun, Han, Xu, Wang, Jun, Liu, Xiao, Yan, Maoxiao, Wang, Yunxiu, Liu, Hongyan, Shi, Huiling, Gao, Xiaoqing, Ouyang, Chuan, Fu, Xue, Zhang, Xinxin, Liu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835798/
https://www.ncbi.nlm.nih.gov/pubmed/33510775
http://dx.doi.org/10.3389/fgene.2020.622671

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