Cargando…

NECTIN4: A Novel Therapeutic Target for Melanoma

Malignant melanoma is the most common lethal skin cancer and causes death in a short time when metastasized. Although BRAF inhibitors (BRAFi) have greatly improved the prognosis of BRAF-mutated melanoma, drug resistance is a major concern even when they are combined with MEK inhibitors. Alternative...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tanaka, Yuka, Murata, Maho, Shen, Che-Hung, Furue, Masutaka, Ito, Takamichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835875/ https://www.ncbi.nlm.nih.gov/pubmed/33478111 http://dx.doi.org/10.3390/ijms22020976

Ejemplares similares

Nectin Cell Adhesion Molecule 4 (NECTIN4) Expression in Cutaneous Squamous Cell Carcinoma: A New Therapeutic Target?
por: Tanaka, Yuka, et al.
Publicado: (2021)

NECTIN4 Expression in Extramammary Paget’s Disease: Implication of a New Therapeutic Target
por: Murata, Maho, et al.
Publicado: (2020)

Nectin cell adhesion molecule 4 regulates angiogenesis through Src signaling and serves as a novel therapeutic target in angiosarcoma
por: Tanaka, Yuka, et al.
Publicado: (2022)

Immunohistochemical BRAF V600E Expression and Intratumor BRAF V600E Heterogeneity in Acral Melanoma: Implication in Melanoma-Specific Survival
por: Ito, Takamichi, et al.
Publicado: (2020)

OVOL2-Mediated ZEB1 Downregulation May Prevent Promotion of Actinic Keratosis to Cutaneous Squamous Cell Carcinoma
por: Murata, Maho, et al.
Publicado: (2020)

Intra- and Inter-Tumor BRAF Heterogeneity in Acral Melanoma: An Immunohistochemical Analysis
por: Ito, Takamichi, et al.
Publicado: (2019)

Baicalein Inhibits Benzo[a]pyrene-Induced Toxic Response by Downregulating Src Phosphorylation and by Upregulating NRF2-HMOX1 System
por: Tanaka, Yuka, et al.
Publicado: (2020)

The EGFR-ERK/JNK-CCL20 Pathway in Scratched Keratinocytes May Underpin Koebnerization in Psoriasis Patients
por: Furue, Kazuhisa, et al.
Publicado: (2020)

Indirubin-pregnane X receptor-JNK axis accelerates skin wound healing
por: Tanaka, Yuka, et al.
Publicado: (2019)

Narrow-Margin Excision for Invasive Acral Melanoma: Is It Acceptable?
por: Ito, Takamichi, et al.
Publicado: (2020)

Preoperative Screening CT and PET/CT Scanning for Acral Melanoma: Is it Necessary?
por: Ide, Taketoshi, et al.
Publicado: (2021)

S100A6 and c-Kit-Positive Spindle Cell Melanoma of the Dorsal Foot
por: Mitamura, Yasutaka, et al.
Publicado: (2014)

Nectin4 is a potential therapeutic target for asthma
por: Lee, Pureun-Haneul, et al.
Publicado: (2022)

Periostin Links Skin Inflammation to Melanoma Progression in Humans and Mice
por: Ohno, Fumitaka, et al.
Publicado: (2019)

Human epidermal growth factor receptor 3 serves as a novel therapeutic target for acral melanoma
por: Tanaka, Yuka, et al.
Publicado: (2023)

The Outcome of Chemotherapy for Metastatic Extramammary Paget’s Disease
por: Hashimoto, Hiroki, et al.
Publicado: (2021)

Mucosal Invasion, but Not Incomplete Excision, Has Negative Impact on Long-Term Survival in Patients With Extramammary Paget’s Disease
por: Hashimoto, Hiroki, et al.
Publicado: (2021)

Poroma with Sebaceous Differentiation: Dermoscopy for the Diagnosis of Skin Tumor with Sebaceous Differentiation
por: Ito, Takamichi, et al.
Publicado: (2015)

Aryl Hydrocarbon Receptor Activation Downregulates IL-33 Expression in Keratinocytes via Ovo-Like 1
por: Tsuji, Gaku, et al.
Publicado: (2020)

Diagnostic and Prognostic Roles of Urine Nectin-2 and Nectin-4 in Human Bladder Cancer
por: Miyake, Makito, et al.
Publicado: (2023)

Linear and Whorled Nevoid Hypermelanosis With Tetralogy of Fallot
por: Ito, Takamichi, et al.
Publicado: (2015)

Regulation of Skin Barrier Function via Competition between AHR Axis versus IL-13/IL-4‒JAK‒STAT6/STAT3 Axis: Pathogenic and Therapeutic Implications in Atopic Dermatitis
por: Furue, Masutaka
Publicado: (2020)

p63-dependent and independent mechanisms of nectin-1 and nectin-4 regulation in the epidermis
por: Mollo, Maria Rosaria, et al.
Publicado: (2015)

The Clinical and Histopathological Features of Cutaneous Immune-Related Adverse Events and Their Outcomes
por: Hashimoto, Hiroki, et al.
Publicado: (2021)

Antiphospholipid Syndrome Complicated by Unilateral Pleural Effusion
por: Mitamura, Yasutaka, et al.
Publicado: (2013)

Trop2 Expression in Extramammary Paget’s Disease and Normal Skin
por: Ito, Takamichi, et al.
Publicado: (2021)

Expression of nectin-4 in prostate cancer
por: Ordu, Melike, et al.
Publicado: (2023)

CDK4: A Novel Therapeutic Target for Extramammary Paget’s Disease
por: Hashimoto, Hiroki, et al.
Publicado: (2021)

Tracing the evolution of nectin and nectin-like cell adhesion molecules
por: Duraivelan, Kheerthana, et al.
Publicado: (2020)

Tryptophan Photoproduct FICZ Upregulates IL1A, IL1B, and IL6 Expression via Oxidative Stress in Keratinocytes
por: Tanaka, Yuka, et al.
Publicado: (2018)

Four Cases of Successfully Treated Chronic Expanding Soft Tissue Hematoma
por: Ito, Takamichi, et al.
Publicado: (2014)

Nectin like-5 overexpression correlates with the malignant phenotype in cutaneous melanoma
por: Bevelacqua, Valentina, et al.
Publicado: (2012)

Regulation of Filaggrin, Loricrin, and Involucrin by IL-4, IL-13, IL-17A, IL-22, AHR, and NRF2: Pathogenic Implications in Atopic Dermatitis
por: Furue, Masutaka
Publicado: (2020)

Clinical Condition and Management of 114 Mamushi (Gloydius blomhoffii) Bites in a General Hospital in Japan
por: Chiba, Takahito, et al.
Publicado: (2017)

Nail Apparatus Melanoma: Current Management and Future Perspectives
por: Ito, Takamichi, et al.
Publicado: (2023)

p16(INK4a) Expression in Porokeratosis
por: Uryu, Miki, et al.
Publicado: (2017)

Increased levels of nectin-4 as a serological marker for pre-eclampsia
por: Yoshizawa, Hikari, et al.
Publicado: (2023)

Nectin expression in pancreatic adenocarcinoma: nectin-3 is associated with a poor prognosis
por: Izumi, Hideki, et al.
Publicado: (2015)

The Systematic Landscape of Nectin Family and Nectin-Like Molecules: Functions and Prognostic Value in Low Grade Glioma
por: Han, Yunhe, et al.
Publicado: (2021)

TROP2 Expression in Sebaceous and Sweat Gland Carcinoma
por: Ito, Takamichi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9uqm1geq2obn9lprf67i9urpd1