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Kinetic, Structural, and Mutational Analysis of Acyl-CoA Carboxylase From Thermobifida fusca YX

Acyl-CoA carboxylases (AcCCase) are biotin-dependent enzymes that are capable of carboxylating more than one short chain acyl-CoA substrate. We have conducted structural and kinetic analyses of such an AcCCase from Thermobifida fusca YX, which exhibits promiscuity in carboxylating acetyl-CoA, propio...

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Detalles Bibliográficos
Autores principales: Shivaiah, Kiran-Kumar, Upton, Bryon, Nikolau, Basil J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835884/
https://www.ncbi.nlm.nih.gov/pubmed/33511159
http://dx.doi.org/10.3389/fmolb.2020.615614