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Natural Polyhydroxy Flavonoids, Curcuminoids, and Synthetic Curcumin Analogs as α7 nAChRs Positive Allosteric Modulators

The α7 nicotinic acetylcholine receptor (α7 nAChR) is a ligand-gated ion channel that is involved in cognition disorders, schizophrenia, pain, and inflammation. Allosteric modulation of this receptor might be advantageous to reduce the toxicity in comparison with full agonists. Our previous results...

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Detalles Bibliográficos
Autores principales: Ximenis, Marta, Mulet, José, Sala, Salvador, Sala, Francisco, Criado, Manuel, González-Muñiz, Rosario, Pérez de Vega, María Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835927/
https://www.ncbi.nlm.nih.gov/pubmed/33478095
http://dx.doi.org/10.3390/ijms22020973

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