Unlike its Paralog LEDGF/p75, HRP-2 Is Dispensable for MLL-R Leukemogenesis but Important for Leukemic Cell Survival

HDGF-related protein 2 (HRP-2) is a member of the Hepatoma-Derived Growth Factor-related protein family that harbors the structured PWWP and Integrase Binding Domain, known to associate with methylated histone tails or cellular and viral proteins, respectively. Interestingly, HRP-2 is a paralog of L...

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Detalles Bibliográficos
Autores principales: Van Belle, Siska, El Ashkar, Sara, Čermáková, Kateřina, Matthijssens, Filip, Goossens, Steven, Canella, Alessandro, Hodges, Courtney H., Christ, Frauke, De Rijck, Jan, Van Vlierberghe, Pieter, Veverka, Václav, Debyser, Zeger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835958/
https://www.ncbi.nlm.nih.gov/pubmed/33477970
http://dx.doi.org/10.3390/cells10010192

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