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Biological Activities of Some New Secondary Metabolites Isolated from Endophytic Fungi: A Review Study

Secondary metabolites isolated from plant endophytic fungi have been getting more and more attention. Some secondary metabolites exhibit high biological activities, hence, they have potential to be used for promising lead compounds in drug discovery. In this review, a total of 134 journal articles (...

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Detalles Bibliográficos
Autores principales: Zheng, Ruihong, Li, Shoujie, Zhang, Xuan, Zhao, Changqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835970/
https://www.ncbi.nlm.nih.gov/pubmed/33478038
http://dx.doi.org/10.3390/ijms22020959
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author Zheng, Ruihong
Li, Shoujie
Zhang, Xuan
Zhao, Changqi
author_facet Zheng, Ruihong
Li, Shoujie
Zhang, Xuan
Zhao, Changqi
author_sort Zheng, Ruihong
collection PubMed
description Secondary metabolites isolated from plant endophytic fungi have been getting more and more attention. Some secondary metabolites exhibit high biological activities, hence, they have potential to be used for promising lead compounds in drug discovery. In this review, a total of 134 journal articles (from 2017 to 2019) were reviewed and the chemical structures of 449 new metabolites, including polyketides, terpenoids, steroids and so on, were summarized. Besides, various biological activities and structure-activity relationship of some compounds were aslo described.
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spelling pubmed-78359702021-01-27 Biological Activities of Some New Secondary Metabolites Isolated from Endophytic Fungi: A Review Study Zheng, Ruihong Li, Shoujie Zhang, Xuan Zhao, Changqi Int J Mol Sci Review Secondary metabolites isolated from plant endophytic fungi have been getting more and more attention. Some secondary metabolites exhibit high biological activities, hence, they have potential to be used for promising lead compounds in drug discovery. In this review, a total of 134 journal articles (from 2017 to 2019) were reviewed and the chemical structures of 449 new metabolites, including polyketides, terpenoids, steroids and so on, were summarized. Besides, various biological activities and structure-activity relationship of some compounds were aslo described. MDPI 2021-01-19 /pmc/articles/PMC7835970/ /pubmed/33478038 http://dx.doi.org/10.3390/ijms22020959 Text en © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zheng, Ruihong
Li, Shoujie
Zhang, Xuan
Zhao, Changqi
Biological Activities of Some New Secondary Metabolites Isolated from Endophytic Fungi: A Review Study
title Biological Activities of Some New Secondary Metabolites Isolated from Endophytic Fungi: A Review Study
title_full Biological Activities of Some New Secondary Metabolites Isolated from Endophytic Fungi: A Review Study
title_fullStr Biological Activities of Some New Secondary Metabolites Isolated from Endophytic Fungi: A Review Study
title_full_unstemmed Biological Activities of Some New Secondary Metabolites Isolated from Endophytic Fungi: A Review Study
title_short Biological Activities of Some New Secondary Metabolites Isolated from Endophytic Fungi: A Review Study
title_sort biological activities of some new secondary metabolites isolated from endophytic fungi: a review study
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835970/
https://www.ncbi.nlm.nih.gov/pubmed/33478038
http://dx.doi.org/10.3390/ijms22020959
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